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TMED3 Antibody

  • 中文名稱：
    TMED3兔多克隆抗體
  • 貨號(hào)：
    CSB-PA917113
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA917113(TMED3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TMED3
  • 別名：
    C15orf22 antibody; Integral type I protein antibody; Membrane protein p24B antibody; p24 family protein gamma 4 antibody; p24 family protein gamma-4 antibody; P24B antibody; p24g4 antibody; p24gamma4 antibody; p26 antibody; Testis tissue sperm binding protein Li 48e antibody; Tmed3 antibody; TMED3_HUMAN antibody; Transmembrane emp24 domain containing protein 3 antibody; Transmembrane emp24 domain-containing protein 3 antibody; Transmembrane p24 trafficking protein 3 antibody; UNQ5357/PRO1078 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human TMED3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network.
  • 基因功能參考文獻(xiàn)：
    1. Study demonstrates that transmembrane p24 trafficking protein 3 (TMED3) promotes hepatocellular carcinoma (HCC) metastasis and is a potential prognostic biomarker in hepatocellular carcinoma. Study propose that TMED3 promotes HCC metastasis through IL-11/STAT3 signaling. PMID: 27901021
    2. This genome-wide screen has identified two novel metastatic suppressors: TMED3 and SOX12, the knockdown of which increases metastatic growth after direct seeding. PMID: 24920608
  • 亞細(xì)胞定位：
    Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    EMP24/GP25L family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 28889

    KEGG: hsa:23423

    STRING: 9606.ENSP00000299705

    UniGene: Hs.513058