Your Good Partner in Biology Research

TMTC1 Antibody, HRP conjugated

  • 中文名稱:
    TMTC1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA808537LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TMTC1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TMTC1
  • 別名:
    TMTC1 antibody; ARG99 antibody; Protein O-mannosyl-transferase TMTC1 antibody; EC 2.4.1.109 antibody; Transmembrane and TPR repeat-containing protein 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Transmembrane and TPR repeat-containing protein 1 protein (1-227AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產品評價

靶點詳情

  • 功能:
    Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3.
  • 基因功能參考文獻:
    1. O-mannosylation pathway dedicated to cadherins/ protocadherins orchestrated by the four TMTC1-4 genes PMID: 28973932
    2. findings provide an important link between aneuploidy and the stress pathways activated by Aurora B inhibition and also support the use of Aurora B inhibitors in combination therapy for treatment of cancer. PMID: 24764305
  • 亞細胞定位:
    Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
  • 蛋白家族:
    TMTC family
  • 數據庫鏈接:

    HGNC: 24099

    OMIM: 615855

    KEGG: hsa:83857

    STRING: 9606.ENSP00000442046

    UniGene: Hs.401954