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TOB2 Antibody

  • 中文名稱：
    TOB2兔多克隆抗體
  • 貨號：
    CSB-PA617901ESR1HU
  • 規(guī)格：
    ￥440
  • 促銷：
    小規(guī)格抗體限時一口價
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA617901ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA617901ESR1HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TOB2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TOB2
  • 別名：
    KIAA1663 antibody; Protein Tob2 antibody; Protein Tob4 antibody; Tob2 antibody; TOB2_HUMAN antibody; TOB4 antibody; Transducer of erbB 2 2 antibody; Transducer of erbB-2 2 antibody; Transducer of ERBB2, 2 antibody; TROB2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Protein Tob2 protein (1-70AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases.
  • 基因功能參考文獻：
    1. Results show reduced Tob2 expression in primary hepatocellular Carcinoma cells (HCC) and that dysregulation of miR-362 and Tob2 may contribute to HCC malignancy. PMID: 25649327
    2. study identifies miR-378-TOB2-cyclin D1 as a functional module to mediate the cross talk between Myc and Ras signaling in cellular transformation PMID: 21242960
    3. TNFalpha is able to transactivate ErbB-2 and use it as an obligatory downstream signaling molecule in the generation of mitogenic signals. PMID: 19760502
    4. Haploinsufficiency of the MLL and TOB2 genes in lymphoid malignancy. PMID: 19940862
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    BTG family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11980

    OMIM: 607396

    KEGG: hsa:10766

    STRING: 9606.ENSP00000331305

    UniGene: Hs.474978