TPT1 Antibody, FITC conjugated
-
中文名稱:TPT1兔多克隆抗體, FITC偶聯(lián)
-
貨號:CSB-PA024134LC01HU
-
規(guī)格:¥880
-
其他:
產品詳情
-
產品名稱:Rabbit anti-Homo sapiens (Human) TPT1 Polyclonal antibody
-
Uniprot No.:
-
基因名:TPT1
-
別名:FLJ27337 antibody; Fortilin antibody; Histamine releasing factor antibody; Histamine-releasing factor antibody; HRF antibody; Immunoglobulin E-dependent antibody; p02 antibody; p23 antibody; TCTP antibody; TCTP_HUMAN antibody; tpt1 antibody; Translationally controlled tumor protein antibody; Translationally-controlled tumor protein antibody; Tumor protein translationally controlled 1 antibody; tumor protein; translationally-controlled 1 antibody
-
宿主:Rabbit
-
反應種屬:Human
-
免疫原:Recombinant Human Translationally-controlled tumor protein (1-172AA)
-
免疫原種屬:Homo sapiens (Human)
-
標記方式:FITC
-
克隆類型:Polyclonal
-
抗體亞型:IgG
-
純化方式:>95%, Protein G purified
-
濃度:It differs from different batches. Please contact us to confirm it.
-
保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式:Liquid
-
儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關產品
靶點詳情
-
功能:Involved in calcium binding and microtubule stabilization.
-
基因功能參考文獻:
- Study findings suggested that TCTP promotes colorectal cancer metastasis through regulating the behaviors of HMGB1 and the downstream activation of the NF-kappaB signaling pathway. PMID: 30066846
- The biological effects of Na,K-ATPase and TCTP interaction are reviewed. PMID: 29867020
- The cells knocked down for TCTP show diminished invasiveness and migration under TGF-beta1 treatment. TGF-beta1 dependent TCTP expression is required for epithelial to mesenchymal transition in cells. PMID: 28958626
- that TPT1 knockdown altered the BECN1 interactome, a representative MTOR-independent pathway, to stimulate autophagosome formation PMID: 28409693
- Transfection with TCTP-Lipid modified antisense oligonucleotides led to rapid and prolonged internalization via macropinocytosis, TCTP downregulation and significant decreased cell viability in in castration-resistant prostate cancer cells. PMID: 28472637
- extracellular TCTP has a role as a promoter of colorectal cancer progression and liver metastases via Cdc42/JNK/MMP9 activation PMID: 27367023
- The structure of human HRF (hHRF) was solved in 2 new crystal forms, one at the highest resolution (1.4A) yet reported. The high resolution hHRF structure reveals a disulphide-linked dimer, in which the 2 molecules are closely associated and provides a model for the role of HRF in mast cell activation. PMID: 29216544
- analyzed the interactome of TCTP in HeLa cells by coimmunoprecipitation (IP) and mass spectrometry (MS). Results not only reveal a large number of TCTP-associated proteins that possess pleiotropic functions, but also provide novel insights into the molecular mechanisms of TCTP in tumorigenesis PMID: 27607350
- Fortilin directly interacts with the cytoplasmic domain of IRE1alpha, inhibits both kinase and endoribonuclease (RNase) activities of this stress sensor, and protects cells against apoptotic cell death at both cellular and whole animal levels. PMID: 28550308
- These findings provide novel data on the role and regulation of TCTP in skeletal muscle in vivo. PMID: 27813490
- TCTP may thus contribute to the development of anti-cancer drug resistance. PMID: 28143584
- The findings suggest that the synergistic actions of Histamine Releasing Factor and Histamine Releasing Factor-reactive IgE may play important roles in the pathogenesis of Chronic Urticaria. PMID: 28219065
- Downregulation of the expression of TCTP inhibits the migration and invasion of glioma cells. PMID: 26328748
- These data may suggest an involvement of translationally controlled tumor protein in normal physiology and carcinogenesis. PMID: 26425551
- High HRF expression is associated with non-Hodgkin lymphomas. PMID: 25363345
- Results demonstrate that TCTP mRNA translation is regulated by signalling through the PI3-K/Akt/mTORC1 pathway in neoplasms. PMID: 25936523
- High phospho-TCTP expression levels are associated with aggressive breast cancer. PMID: 25779659
- TCTP binds to hemin and functions as a "buffer protein", controlling cellular homeostasis. PMID: 25396429
- analysis of how TCTP-PTD penetrates A549 human lung cancer cell membranes and promotes protein internalization PMID: 25423047
- Data indicate that Tanshinone IIA (Tan-IIA)T upregulated the protein expression of CHOP and Bax, but downregulated the protein expression of BiP, TCTP, Mcl-1 and Bcl-xL. PMID: 25270224
- Targeting Hsp27 interaction with TCTP, a partner protein identified in a genetic screen, increases therapy sensitivity, and could decrease or abolish toxicity to normal cells. PMID: 25277244
- TCTP is functionally implicated in the progression of NF1-associated tumors. PMID: 25092287
- osteoclastogenic activity of translationally-controlled tumor protein (TCTP) with reciprocal repression of p21 PMID: 25263704
- Interaction of translationally controlled tumor protein with Apaf-1 is involved in the development of chemoresistance in HeLa cells. PMID: 24606760
- High TCTP expression is associated with glioma. PMID: 24311645
- Plasmodium falciparum TCTP showed a lower B cell proliferative effect than human TCTP. PMID: 24465583
- Cofilin-1 expression positively correlates with the tumor grade, and p23 expression correlates with the endoplasmic reticulum positive status. PMID: 24106833
- TCTP is a novel mediator of endothelial prosurvival and growth in patients with pulmonary arterial hypertension. PMID: 24657995
- observations indicate that TCTP enhances Pim-3 stability to simultaneously promote and prevent cell-cycle progression and apoptosis, respectively PMID: 24165482
- TCTP may have a role in prostate cancer development PMID: 23894469
- Data indicate that translationally controlled tumor protein (TCTP) expression in glioma was an independent prognostic factor, which might be a potential diagnostic and therapeutic target of glioma. PMID: 23749504
- TCTP binds to the beta domain of VHL through competition with HIF1alpha, which promotes VHL degradation by the ubiquitin-proteasome system and HIF1alpha stability. PMID: 23387829
- human miR-27b regulates the expression of the TCTP tumor protein, and circulating miR-27b may be useful as a biomarker for oral cancer research. PMID: 22902387
- Demonstrate the presence of TCTP in human cornea, and suggest a potential role in the pathogenesis of herpes virus keratitis. PMID: 22853445
- Results imply that TCTP might be a mediator of PRL-3-promoted proliferation, migration and invasion of human colon cancer cells. PMID: 22340241
- Data suggest that TCTP may play a critical role in maintaining genomic integrity in response to DNA-damaging agents. PMID: 22451927
- CHD1L/TCTP/Cdc25C/Cdk1 molecular pathway causes the malignant transformation of hepatocytes with the phenotypes of accelerated mitotic progression and the production of aneuploidy PMID: 21953552
- The TCTP is a survival factor that protects cancer cells from oxidative stress-induced cell-death. PMID: 21801721
- These results identify TCTP-bearing nanovesicles as a novel component of the paracrine apoptotic program of potential importance in vascular repair. PMID: 20966960
- The Chfr-TCTP interaction was stable throughout the cell cycle, but it could be diminished by the complete depolymerization of the microtubules. PMID: 18504434
- Knockdown of TCTP inhibited proliferation, migration, and invasion activities of LoVo cells in vitro and in vivo. PMID: 19621893
- Data suggest a kind of feedback regulation between TCTP and VDR to regulate a variety of (Ca(2+) dependent) cellular effects and in this way further underscore the physiological relevance of the observed physical interaction beteen TCTP and VDR. PMID: 19815065
- The mRNA of the translationally controlled tumor protein P23/TCTP is a highly structured RNA, which activates the dsRNA-dependent protein kinase PKR (TCTP PROTEIN) PMID: 11991642
- Physical and functional interaction between myeloid cell leukemia 1 protein (MCL1) and this protein PMID: 12149273
- Human TCTP was identified as a putative Plk-interacting clone by a two-hybrid screen. Plk phosphorylates TCTP on two serine residues in vitro and cofractionates with the majority of kinase activity toward TCTP in mitotic cell lysates. PMID: 12167714
- genetic regulation in tumor reversion PMID: 12399545
- results do not support the hypothesis that IgE(mn+) induces a late allergic reaction (LAR), but do not exclude the alternative hypothesis that HRFs are released during a LAR and contribute to asthma severity PMID: 12487227
- Patients with Multiple drug allergy syndrome and more than 1/3 with hypersensitivity to a single antibacterial drug showed the presence of circulating histamine-releasing factors. Such factors might play a role in drug-induced adverse reactions. PMID: 12876410
- HRF p23 can stimulate nonimmune epithelium such as bronchial epithelium PMID: 12948934
- Human recombinant histamine-releasing factor can partially inhibit the secretion of IL-2 and IL-13 protein in a dose-dependent manner from both purified peripheral blood T cells and Jurkat T cells. PMID: 14500674
顯示更多
收起更多
-
亞細胞定位:Cytoplasm.
-
蛋白家族:TCTP family
-
組織特異性:Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC
-
數(shù)據(jù)庫鏈接:
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-