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TRIM4 Antibody, HRP conjugated

  • 中文名稱：
    TRIM4兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA866336LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TRIM4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TRIM4
  • 別名：
    RING finger protein 87 antibody; RNF 87 antibody; RNF87 antibody; TRIM4 antibody; TRIM4_HUMAN antibody; Tripartite motif containing 4 antibody; Tripartite motif protein 4 antibody; Tripartite motif protein TRIM4 antibody; Tripartite motif-containing protein 4 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase TRIM4 protein (1-118AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    E3 ubiquitin-protein ligase. Mediates 'Lys-63'-linked polyubiquitination of the innate immune receptor DDX58, this linkage doesn't lead to proteasomal degradation but seems to enhance IFN induction.
  • 基因功能參考文獻(xiàn)：
    1. TRIM4 is an important regulator of the virus-induced interferon induction pathways by mediating RIG-I for K63-linked ubiquitination. PMID: 24755855
    2. ZNF198-FGFR1 is associated with phosphorylation of several proteins including SSBP2, ABL, FLJ14235, CALM and TRIM4 proteins. PMID: 19658100
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    TRIM/RBCC family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16275

    KEGG: hsa:89122

    STRING: 9606.ENSP00000348216

    UniGene: Hs.50749