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VKORC1L1 Antibody

  • 中文名稱：
    VKORC1L1兔多克隆抗體
  • 貨號：
    CSB-PA818673LA01HU
  • 規(guī)格：
    ￥440
  • 促銷：
    小規(guī)格抗體限時一口價
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA818673LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human stomach tissue using CSB-PA818673LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) VKORC1L1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    VKORC1L1
  • 別名：
    VKORC1L1; Vitamin K epoxide reductase complex subunit 1-like protein 1; VKORC1-like protein 1
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Vitamin K epoxide reductase complex subunit 1-like protein 1 protein (38-91AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，VKORC1L1 Antibody (CSB-PA818673LA01HU)，的標記方式是Non-conjugated。對于VKORC1L1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA818673LB01HU VKORC1L1 Antibody, HRP conjugated ELISA
    FITC CSB-PA818673LC01HU VKORC1L1 Antibody, FITC conjugated
    Biotin CSB-PA818673LD01HU VKORC1L1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K (in vitro), and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins.
  • 基因功能參考文獻：
    1. This study showed that polymorphisms of EPHX1 and VKORC1L1 could be determinants of stable warfarin doses. PMID: 29054760
    2. a concerted action of the four conserved cysteines of VKORC1L1 for active site regeneration PMID: 24532791
    3. VKORC1L1 is responsible for driving vitamin K-mediated intracellular antioxidation pathways critical to cell survival. PMID: 21367861
    4. VKORC1L1 does not affect the variability of warfarin dose requirement in a Japanese patient population PMID: 17996924
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    VKOR family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 21492

    OMIM: 608838

    KEGG: hsa:154807

    STRING: 9606.ENSP00000353998

    UniGene: Hs.427232