XAB2 Antibody
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貨號:CSB-PA862073LA01HU
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規(guī)格:¥440
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促銷:
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圖片:
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Western Blot
Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate, A549 whole cell lysate
All lanes: XAB2 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 101 kDa
Observed band size: 101 kDa -
IHC image of CSB-PA862073LA01HU diluted at 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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IHC image of CSB-PA862073LA01HU diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Immunofluorescence staining of PC-3 cells with CSB-PA862073LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) XAB2 Polyclonal antibody
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Uniprot No.:
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基因名:XAB2
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別名:0610041O14Rik antibody; adapter protein ATH 55 antibody; Adapter protein ATH-55 antibody; Ath55 antibody; AV025587 antibody; Crn related protein kim1 antibody; crn-related protein kim1 antibody; DKFZp762C1015 antibody; HCNP antibody; HCNP protein antibody; HCRN antibody; KIAA1177 antibody; NTC90 antibody; PP3898 antibody; Pre-mRNA-splicing factor SYF1 antibody; Protein HCNP antibody; RNA splicing factor antibody; SYF1 antibody; SYF1 homolog antibody; SYF1 homolog, RNA splicing factor antibody; SYF1 pre mRNA splicing factor antibody; SYF1_HUMAN antibody; Xab2 antibody; XPA binding protein 2 antibody; XPA-binding protein 2 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human Pre-mRNA-splicing factor SYF1 protein (750-840AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
本頁面中的產(chǎn)品,XAB2 Antibody (CSB-PA862073LA01HU),的標(biāo)記方式是Non-conjugated。對于XAB2 Antibody,我們還提供其他標(biāo)記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, WB, IHC, IF
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:5000 IHC 1:200-1:500 IF 1:50-1:200 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點詳情
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功能:Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing.
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基因功能參考文獻(xiàn):
- these results support a novel function of XAB2 in mitotic cell cycle regulation, which is partially mediated by transcription regulation on CENPE. PMID: 27735937
- we suggest that the XAB2 complex mediates DNA damage response events important for the end resection step of homologous recombination , and speculate that its adjacent-localization relative to double-strand break marked by gH2AX is important for this function PMID: 27084940
- Study identifies XAB2 tagSNPs (rs794078 and rs4134816) significantly associated with the risk of non-small cell lung cancer (NSCLC) in Chinese population, which supports XAB2 playing significant role in the development of NSCLC. PMID: 26228655
- Hematopoietic myeloid cell differentiation diminishes nucleotide excision repair and XAB2 expression. PMID: 25027282
- XAB2 complex is a multifunctional factor involved in pre-mRNA splicing, transcription, and transcription-coupled DNA repair. PMID: 17981804
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亞細(xì)胞定位:Nucleus.
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蛋白家族:Crooked-neck family
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數(shù)據(jù)庫鏈接:
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