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YIPF3 Antibody, Biotin conjugated

  • 中文名稱(chēng)：
    YIPF3兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA863928LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) YIPF3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    YIPF3
  • 別名：
    YIPF3; C6orf109; KLIP1; Protein YIPF3; Killer lineage protein 1; Natural killer cell-specific antigen KLIP1; YIP1 family member 3
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Protein YIPF3 protein (2-148AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
  • 基因功能參考文獻(xiàn)：
    1. The significance of YIPF3 protein for the maintenance of the morphology of the Golgi was tested by RNA interference, revealing a number of specific morphological changes to this organelle on their depletion. PMID: 27999994
    2. Knockdown of YIPF1 and YIPF2, but not that of YIPF6, also reduced intracellular glycans in HT-29 cells. Thus, we confirmed that YIPF1, YIPF2, and YIPF6 play a significant role in supporting normal glycan synthesis PMID: 28286305
    3. YIPF3 is synthesized in the ER as a N-glycosylated form (40 kDa), is then O-glycosylated in the Golgi apparatus to become a lower mobility form (46 kDa) and finally becomes a higher mobility form cleaved at its C-terminal luminal domain (36 kDa). PMID: 21757827
    4. identification and characterization of KLIP-1, a novel transmembrane protein whose expression correlates with hematopoietic activity PMID: 12490290
  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein. Cytoplasm. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Note=Localization to the cytoplasm or to the cell membrane is developmentally and ontogenetically regulated.
  • 蛋白家族：
    YIP1 family
  • 組織特異性：
    Expressed by nucleated hematopoietic cells (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 21023

    OMIM: 609775

    KEGG: hsa:25844

    STRING: 9606.ENSP00000361499

    UniGene: Hs.440950