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YY1AP1 Antibody, FITC conjugated

  • 中文名稱:
    YY1AP1兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào):
    CSB-PA884488LC01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) YY1AP1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    YY1AP1
  • 別名:
    FLJ10875 antibody; FLJ13914 antibody; GRNG antibody; HCCA1 antibody; HCCA2 antibody; Hepatocellular carcinoma susceptibility protein antibody; Hepatocellular carcinoma-associated protein 2 antibody; OTTHUMP00000033475 antibody; OTTHUMP00000033476 antibody; OTTHUMP00000200831 antibody; OTTHUMP00000200832 antibody; OTTHUMP00000200833 antibody; OTTHUMP00000200836 antibody; YAP antibody; YY1-associated protein 1 antibody; YY1AP antibody; YY1AP1 antibody; YYAP1_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human YY1-associated protein 1 protein (335-466AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication. Enhances transcription activation by YY1. Plays a role in cell cycle regulation.
  • 基因功能參考文獻(xiàn):
    1. Data indicate WW-binding protein 2 (WBP2) as an important co-factor of YY1 associated protein 1 (YAP) that enhances YAP/TEAD-mediated gene transcription. PMID: 28332498
    2. Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease. PMID: 27939641
    3. YY1AP1 may serve as a key molecular target for EpCAM(+) AFP(+) HCC subtype PMID: 25597408
    4. human liver cancer associated gene PMID: 11856496
    5. YY1AP is a novel co-activator of YY1 PMID: 14744866
    6. HCCA2 may play a novel role in cell cycle regulation. PMID: 17541814

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  • 相關(guān)疾?。?/div>
    Grange syndrome (GRNG)
  • 亞細(xì)胞定位:
    Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus.
  • 組織特異性:
    Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 30935

    OMIM: 602531

    KEGG: hsa:55249

    STRING: 9606.ENSP00000357323

    UniGene: Hs.584927