ZDHHC20 Antibody
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中文名稱:ZDHHC20兔多克隆抗體
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貨號:CSB-PA722800LA01HU
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規(guī)格:¥440
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促銷:
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圖片:
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) ZDHHC20 Polyclonal antibody
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Uniprot No.:
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基因名:ZDHHC20
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別名:ZDHHC20; Palmitoyltransferase ZDHHC20; Acyltransferase ZDHHC20; DHHC domain-containing cysteine-rich protein 20; DHHC20; Zinc finger DHHC domain-containing protein 20
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宿主:Rabbit
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反應種屬:Human
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免疫原:Recombinant Human Probable palmitoyltransferase ZDHHC20 protein (75-130AA)
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免疫原種屬:Homo sapiens (Human)
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標記方式:Non-conjugated
本頁面中的產(chǎn)品,ZDHHC20 Antibody (CSB-PA722800LA01HU),的標記方式是Non-conjugated。對于ZDHHC20 Antibody,我們還提供其他標記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
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應用范圍:ELISA, IF
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推薦稀釋比:
Application Recommended Dilution IF 1:50-1:200 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關產(chǎn)品
靶點詳情
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功能:Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates. Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation. Has a preference for acyl-CoA with C16 fatty acid chains. Can also utilize acyl-CoA with C14 and C18 fatty acid chains.
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基因功能參考文獻:
- crystal structure determined; active site resides at the membrane-cytosol interface; acyl chain binds in a cavity formed by the transmembrane domain; propose a mechanism for acyl chain-length selectivity in DHHC enzymes on the basis of cavity mutants with preferences for shorter and longer acyl chains PMID: 29326245
- Targeting of a peripheral modulator of EGFR signaling, DHHC20, causes a loss of signal regulation and susceptibility to EGFR inhibitor-induced cell death. PMID: 27153536
- DHHC20 is a human N-terminal-myristoyl-directed palmitoyl acyltransferase involved in cellular transformation, that may play a role in cancer. PMID: 20334580
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亞細胞定位:Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region.
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蛋白家族:DHHC palmitoyltransferase family
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數(shù)據(jù)庫鏈接:
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