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vcp Antibody

  • 中文名稱：
    vcp兔多克隆抗體
  • 貨號(hào)：
    CSB-PA772050LA01DIL
  • 規(guī)格：
    ￥440
  • 促銷：
    小規(guī)格抗體限時(shí)一口價(jià)
  • 圖片：
    • Western Blot
      Positive WB detected in: Zebrafish tissue, Zebrafish brain tissue, Zebrafish heart tissue, Zebrafish eye tissue
      All lanes: vcp antibody at 1.8μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 90 kDa
      Observed band size: 90 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) vcp Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    vcp antibody; cdc48 antibody; si:ch211-113n10.2Transitional endoplasmic reticulum ATPase antibody; TER ATPase antibody; EC 3.6.4.6 antibody; Protein CDC48 antibody; Valosin-containing protein antibody; VCP antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Zebrafish
  • 免疫原：
    Recombinant Zebrafish Transitional endoplasmic reticulum ATPase protein (704-806AA)
  • 免疫原種屬：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，vcp Antibody (CSB-PA772050LA01DIL)，的標(biāo)記方式是Non-conjugated。對(duì)于vcp Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA772050LB01DIL vcp Antibody, HRP conjugated ELISA
    FITC CSB-PA772050LC01DIL vcp Antibody, FITC conjugated
    Biotin CSB-PA772050LD01DIL vcp Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Also involved in DNA damage response: recruited to double-strand breaks (DSBs) sites and promotes the recruitment of tp53bp1 at DNA damage sites. Together with sprtn metalloprotease, involved in the repair of covalent DNA-protein cross-links (DPCs) during DNA synthesis. Involved in interstrand cross-link repair in response to replication stress by mediating unloading of the ubiquitinated CMG helicase complex. Enhances cell cycle progression and inhibits apoptosis at low temperatures. Essential for the maturation of ubiquitin-containing autophagosomes and the clearance of ubiquitinated protein by autophagy. Acts as a negative regulator of type I interferon production by promoting ubiquitination of ddx58/rig-i. May play a role in the ubiquitin-dependent sorting of membrane proteins to lysosomes where they undergo degradation. May more particularly play a role in caveolins sorting in cells. By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway.
  • 基因功能參考文獻(xiàn)：
    1. When we introduced CDC48 antisense morpholino oligonucleotides into zebrafish embryos, the morphant embryos were lethal and showed defects in neuronal outgrowth and neurodegeneration. PMID: 22549779
    2. CDC48 may promote cell cycling and cell proliferation via C-terminal tyrosine phosphorylation during cold acclimation in fish cells PMID: 12914916
  • 亞細(xì)胞定位：
    Cytoplasm, cytosol. Endoplasmic reticulum. Nucleus.
  • 蛋白家族：
    AAA ATPase family
  • 數(shù)據(jù)庫鏈接：