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Recombinant Cupiennius salei Omega-ctenitoxin-Cs1a

  • 中文名稱：
    Recombinant Cupiennius salei Omega-ctenitoxin-Cs1a,Yeast
  • 貨號(hào)：
    CSB-YP305452CUR
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Cupiennius salei Omega-ctenitoxin-Cs1a,Yeast
  • 貨號(hào)：
    CSB-EP305452CUR
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Cupiennius salei Omega-ctenitoxin-Cs1a,Yeast
  • 貨號(hào)：
    CSB-EP305452CUR-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Cupiennius salei Omega-ctenitoxin-Cs1a,Yeast
  • 貨號(hào)：
    CSB-BP305452CUR
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Cupiennius salei Omega-ctenitoxin-Cs1a,Yeast
  • 貨號(hào)：
    CSB-MP305452CUR
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    ; Omega-ctenitoxin-Cs1a; Omega-CNTX-Cs1a; Toxin CSTX-1) [Cleaved into: Toxin CSTX-2a; Toxin CSTX-2b]
  • 種屬：
    Cupiennius salei (Wandering spider)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    48-121
  • 氨基酸序列
    SCI PKHEECTNDK HNCCRKGLFK LKCQCSTFDD ESGQPTERCA CGRPMGHQAI ETGLNIFRGL FKGKKKNKKT K
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Spider venom toxin that shows calcium channel blocking activity and exhibits cytolytic activity by affecting the outer leaflet curvature and/or pore formation across the membrane. It blocks L-type calcium channels (Cav1/CACNA1) in mammalian neurons at nanomolar concentrations. Furthermore, it produces a slow voltage-independent block of mid/low and high voltage-activated calcium channels in cockroach neurons. Potassium ions, histamine, M-ctenitoxin-Cs1a (AC P83619), CSTX-9 (AC P58604), and CSTX-13 (AC P83919) synergistically increase the insecticidal activity of this toxin. In vivo, it causes paralysis in blow flies and provokes death in drosophila.; blocks voltage-activated calcium channels (Cav). Does not induce cell membrane permeability increase when tested on Xenopus oocytes. No alpha-helical structures are detectable. Is 7-fold less neurotoxic than omega-ctenitoxin-Cs1a on drosophila flies.; blocks voltage-activated calcium channels (Cav). Is 190-fold less neurotoxic than omega-ctenitoxin-Cs1a on drosophila flies.
  • 亞細(xì)胞定位：
    Secreted. Target cell membrane.
  • 蛋白家族：
    Spider toxin CSTX superfamily
  • 組織特異性：
    Expressed by the venom gland.