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Recombinant Danio rerio Clusterin-associated protein 1 homolog (cluap1)

  • 中文名稱：
    Recombinant Danio rerio Clusterin-associated protein 1 homolog(cluap1),Yeast
  • 貨號(hào)：
    CSB-YP801867DIL
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Danio rerio Clusterin-associated protein 1 homolog(cluap1),Yeast
  • 貨號(hào)：
    CSB-EP801867DIL
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Danio rerio Clusterin-associated protein 1 homolog(cluap1),Yeast
  • 貨號(hào)：
    CSB-EP801867DIL-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Danio rerio Clusterin-associated protein 1 homolog(cluap1),Yeast
  • 貨號(hào)：
    CSB-BP801867DIL
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Danio rerio Clusterin-associated protein 1 homolog(cluap1),Yeast
  • 貨號(hào)：
    CSB-MP801867DIL
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    cluap1
  • Uniprot No.：
  • 別名：
    cluap1; zgc:56115Clusterin-associated protein 1 homolog; Qilin
  • 種屬：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-427
  • 氨基酸序列
    MSFRDLRNFT EMMRALGYPR LISMENFRSP NFPLVAEILI WLVKRYEPQM EIPSDVDTES DRVFFIKAVA QFMATKAHVK LNLKRLYQAD GYAVKEMLKI TSILYNAMKT KENAGGDQNN DENSKFKFDL GSKIADLKLA RQLGSEITAK GAALFDLLGQ EEDLRESRTA AIARPLEITE TERAMRAAVK DVTESIQMTK DLLNNVSSDE ASLEAKIEKK KQDLERNQKR LQTLQSVRPA FMDEYEKIEE DLEKQYQTYV EKYRNLSFLE QQLDDYHRVE QERFEEAEMA MKMRQNKLKE EEKRLMRSGV ARDEDSDVDI PEDEGSDSDI DDGQQARPHH PRHTQISGRG GARFIGSMRG GDSEETEDSE IDVDDDDEDD DEDGEEDEEE NEDLDEDNDS LEGSSGKPGR TNQSLHPQIL EESDNDF
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B).
  • 基因功能參考文獻(xiàn)：
    1. Consistent with the knowledge that CLUAP1 plays an important role in cilia function and that cilia are critical to photoreceptor function, our results indicate that hypomorphic mutations in CLUAP1 can result in dysfunctional photoreceptors without systemic abnormalities. This is the first report linking mutations in CLUAP1 to human disease and establishes CLUAP1 as a candidate Leber congenital amaurosis gene PMID: 26820066
    2. We identified a novel mutation in cluap1 and determined that photoreceptor maintenance is dependent on cluap1. PMID: 24970261
  • 亞細(xì)胞定位：
    Nucleus. Cell projection, cilium.
  • 蛋白家族：
    CLUAP1 family
  • 數(shù)據(jù)庫鏈接：