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  4. Recombinant Dermatophagoides pteronyssinus Mite group 2 allergen Der p 2 (DERP2)

Recombinant Dermatophagoides pteronyssinus Mite group 2 allergen Der p 2 (DERP2)

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  • 中文名稱：
    Recombinant Dermatophagoides pteronyssinus Mite group 2 allergen Der p 2(DERP2)
  • 貨號：
    CSB-YP343403DJH
  • 規(guī)格：
    ￥2616
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    DERP2
  • Uniprot No.：
  • 別名：
    DERP2Mite group 2 allergen Der p 2; Allergen Der p II; DPX; allergen Der p 2
  • 種屬：
    Dermatophagoides pteronyssinus (European house dust mite)
  • 蛋白長度：
    Full Length of Mature Protein
  • 來源：
    Yeast
  • 分子量：
    16.1kDa
  • 表達區(qū)域：
    18-146aa
  • 氨基酸序列
    DQVDVKDCANHEIKKVLVPGCHGSEPCIIHRGKPFQLEAVFEANQNTKTAKIEIKASIDGLEVDVPGIDPNACHYMKCPLVKGQQYDIKYTWNVPKIAPKSENVVVTVKVMGDDGVLACAIATHAKIRD
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白標簽：
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產(chǎn)品描述：

    The N-terminal 6xHis tag was fused to the gene fragment corresponding to the 18-146aa of the Dermatophagoides pteronyssinus DERP2 protein and then was cloned into an expression vector. The expression vector was transfected into the yeast cells for expression. The generated product was purified and separated to obtain the recombinant Dermatophagoides pteronyssinus DERP2 protein. Its purity is higher than 90%. This recombinant Dermatophagoides pteronyssinus DERP2 protein showed an apparent molecular weight of about 16 kDa under SDS-PAGE condition.

    DERP2 is a gene encoding a protein named Mite group 2 allergen Der p 2 and belongs NPC2 family. Allergic disease can be characterized as manifestations of an exaggerated inflammatory response to environmental allergens triggers. The house dust mite is a major source of environmental inhalation allergens involved in the pathogenesis of anaphylactic type reactions in humans and animals. Mite allergen Der-p2 (DERP2) is one of the major allergens of the house dust mite, which contributes to TLR4 expression and function in B cells in allergic patients. However, the precise mechanisms of Der-p2 on B cells remain obscure.

  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    NPC2 family