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  4. Recombinant Dictyostelium discoideum Ras-related protein Rab-11A (rab11A)

Recombinant Dictyostelium discoideum Ras-related protein Rab-11A (rab11A)

  • 中文名稱：
    盤基網(wǎng)柄菌rab11A重組蛋白
  • 貨號：
    CSB-YP019153DKK
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    盤基網(wǎng)柄菌rab11A重組蛋白
  • 貨號：
    CSB-EP019153DKK
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    盤基網(wǎng)柄菌rab11A重組蛋白
  • 貨號：
    CSB-EP019153DKK-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    盤基網(wǎng)柄菌rab11A重組蛋白
  • 貨號：
    CSB-BP019153DKK
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    盤基網(wǎng)柄菌rab11A重組蛋白
  • 貨號：
    CSB-MP019153DKK
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    rab11A; rab11; DDB_G0269238; Ras-related protein Rab-11A
  • 種屬：
    Dictyostelium discoideum (Slime mold)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-214
  • 氨基酸序列
    MTSKGSQEEY DYLYKIVLIG DSGVGKSNLL SRFTRNEFSL ETKSTIGVEF ATRTIQTEGK TIKAQVWDTA GQERYRAITS AYYRGAVGAL LVYDIAKQAT YKSVERWILE LRENADRNIE IMLVGNKSDL RHLREVSTDE AKEFSEKHKL TFIETSALDS SNVELAFQNI LTQIYHIMSR PSHSTGPQTT IDSNTETIIL PTTSEPPAAK SGCC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Required for normal contractile vacuole structure and function. Cells expressing a dominant negative rab11A exhibit a more extensive contractile vacuole network and enlarged contractile vacuole bladders. These cells exhibit a functional defect in osmotic regulation where cells immersed in water become rounded and detach from the surface, and contain swollen contractile vacuoles.
  • 基因功能參考文獻：
    1. These findings suggest that P2XA activation results in vacuolar calcium release, which triggers activation of CnrF Rab gtpase activating protein activity and subsequent downregulation of Rab11a to allow vacuole fusion. PMID: 24335649
  • 亞細胞定位：
    Contractile vacuole membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 數(shù)據(jù)庫鏈接：