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  4. Recombinant Drosophila melanogaster FMRFamide-related peptides (Fmrf)

Recombinant Drosophila melanogaster FMRFamide-related peptides (Fmrf)

  • 中文名稱：
    黑腹果蠅FMRFa重組蛋白
  • 貨號：
    CSB-YP016032DLU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅FMRFa重組蛋白
  • 貨號：
    CSB-EP016032DLU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅FMRFa重組蛋白
  • 貨號：
    CSB-EP016032DLU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅FMRFa重組蛋白
  • 貨號：
    CSB-BP016032DLU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅FMRFa重組蛋白
  • 貨號：
    CSB-MP016032DLU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    FMRFa
  • Uniprot No.：
  • 別名：
    FMRFa; Fmrf; CG2346FMRFamide-related peptides [Cleaved into: FMRFamide A; Corticotropin-releasing factor-like; AAMDRY-amide; DPKQDFMRF-amide; TPAEDFMRF-amide; SDNFMRF-amide; SPKQDFMRF-amide; PDNFMRF-amide; SAPQDFVRS-amide; MDSNFIRF-amide]
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Cytoplasmic domain
  • 表達(dá)區(qū)域：
    106-114
  • 氨基酸序列
    SVQDN FMHF
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

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靶點詳情

  • 功能：
    In insects, FMRFamide and related peptides have modulatory actions at skeletal neuromuscular junctions, and peptides that are immunologically related to FMRFamide are released into the circulation from neurohemal organs.
  • 基因功能參考文獻(xiàn)：
    1. Animals mutant for either FMRFamide or for the FMRFamide receptor (FR) have a reduced recovery sleep in response to heat stress. PMID: 25668617
    2. DPKQDFMRFamide induces contractions via a G-protein coupled FMRFamide receptor in muscle cells but does not appear to act via cAMP, cGMP, CaMKII or arachidonic acid. PMID: 24526728
    3. Klu is expressed specifically in the postmitotic Ap4/FMRFa neuron, promoting its differentiation through the initiation of BMP signaling PMID: 23633512
    4. DPKQDFMRFamide modulates both synaptic function and behavior through coincident detection mediated by FMRF receptor and dromyosuppressin receptor-2. PMID: 21048131
    5. Here, we review FMRFamide-containing peptides encoded by the D. melanogaster FMRFamide gene in order to review the data on the expression, regulation, and activity of these peptides as well as acknowledge endeavors required to elucidate FaRP signaling. PMID: 11814637
    6. Supplying FMRFa in neurosecretory cells partially rescues the wit lethal phenotype. PMID: 14507784
    7. hybridization in situ shows a lack of co-localization of mRNAs for the circadian neuropeptide PDF and FMRFamide in brains of the flies Musca domestica and Drosophila melanogaster PMID: 17426155

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  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    FARP (FMRFamide related peptide) family
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG2346

    STRING: 7227.FBpp0087471

    UniGene: Dm.7156