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  4. Recombinant Drosophila melanogaster Myb protein (Myb), partial

Recombinant Drosophila melanogaster Myb protein (Myb), partial

  • 中文名稱：
    黑腹果蠅Myb重組蛋白
  • 貨號：
    CSB-YP356215DLU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅Myb重組蛋白
  • 貨號：
    CSB-EP356215DLU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅Myb重組蛋白
  • 貨號：
    CSB-EP356215DLU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅Myb重組蛋白
  • 貨號：
    CSB-BP356215DLU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅Myb重組蛋白
  • 貨號：
    CSB-MP356215DLU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Myb; CG9045; Myb protein
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    DNA-binding protein that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In follicle cells, the complex plays a central role in the site-specific DNA replication at the chorion loci. During development, the complex represses transcription of developmentally controlled E2F target genes.
  • 基因功能參考文獻：
    1. Myb transcriptionally regulates cytokinesis. PMID: 23438598
    2. Dm myb and grim are both involved in regulating PCD in two distinct settings suggests that these two genes may often work together to mediate PCD. PMID: 22960039
    3. Dampened transcriptional activation by E2F1-DP and Myb-MuvB is important to repress mitosis and coordinate the endocycle transcription. PMID: 21045111
    4. controls G2/M progression by inducing cyclin B expression PMID: 11847115
    5. findings imply that Dm-Myb provides an essential nontranscriptional function during chromosomal replication PMID: 12032301
    6. Drosophila myb exerts opposing effects on S phase, promoting proliferation and suppressing endoreduplication. PMID: 12223407
    7. Role for a Drosophila Myb-containing protein complex in site-specific DNA replication PMID: 12490953
    8. DmMyb activates a repressive complex containing Mip130 into a complex competent to support DNA replication at specific loci in a temporally and developmentally proscribed manner. PMID: 15256498
    9. examination of linking together the Myb and E2F2 complexes in higher-order assembly to specific chromosomal sites for the regulation of transcription PMID: 15545624
    10. The essential roles of Myb are executed as part of a switching mechanism that is dependent on DNA sites and developmental context. PMID: 17978103
    11. Cell cycle specific degradation of Drosophila Myb is likely to be utilized as a key regulatory mechanism in down-regulating the activity of the Myb complex. PMID: 18424081

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  • 亞細胞定位：
    Nucleus. Chromosome.
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG9045

    STRING: 7227.FBpp0089402

    UniGene: Dm.2907