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Recombinant Drosophila melanogaster Protein king tubby (king-tubby)

  • 中文名稱：
    黑腹果蠅ktub重組蛋白
  • 貨號(hào)：
    CSB-YP774782DLU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅ktub重組蛋白
  • 貨號(hào)：
    CSB-EP774782DLU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅ktub重組蛋白
  • 貨號(hào)：
    CSB-EP774782DLU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅ktub重組蛋白
  • 貨號(hào)：
    CSB-BP774782DLU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅ktub重組蛋白
  • 貨號(hào)：
    CSB-MP774782DLU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ktub
  • Uniprot No.：
  • 別名：
    ktub; Tulp; CG9398; Protein king tubby
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-460
  • 氨基酸序列
    MSGINSRNQK MEQQRQLMEA YIRQKRASPG MVQASDLQIN RPMSGMRSNS RELHAYDGPM QFISSPQNPD QILTNGSPGG INPVAMNTSR NHSNNMRSLS TINQEADLIE EISSHELEDE ESSPVTVIEQ HQQSASHSAN STQSQKPRAR QHSFSDNLDE DDYTNRNVAG AAPVRPAGMA SSPYKDATLD GSSNGTGNGT GGESEGDVIG NIDQFVMQPA PQGVLYKCRI TRDRKGMDRG LFPIYYLHLE RDYGKKIFLL GGRKRKKSKT SNYIVSCDPT DLSRNADGFC GKLRSNVFGT SFTVFDNGNK ESTESPRLDL AVIIYDTNIL GFKGPRNMTV ILPGMTEDDQ RVKISSADPK QQGILDLWKM KNMDNIVELH NKTPVWNDET QSYVLNFHGR VTQASVKNFQ LVHDSDPEYI VMQFGRTSED VFTMDYRYPL CAMQAFAIAL SSFDGKIACE
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Functions in regulating protein trafficking, retinal maintenance and lipid storage. Protects photoreceptor cells R1 to R6 against light-induced retinal degeneration by stimulating norpA-mediated endocytosis of the rhodopsin ninaE (Rh1). In the auditory receptor neurons, functions as a cilia trafficking regulator of various transient receptor potential (TRP) channel components including iav and nompC. Likely to deliver pre-ciliary vesicles containing membrane proteins such as iav and nompC to the intraflagellar transport complex (IFT) at the cilia base. Plays a role in the inhibition of fat storage.
  • 基因功能參考文獻(xiàn)：
    1. This is the first demonstration that dTULP regulates TRP channel localization in cilia, and suggests that dTULP is a protein that regulates ciliary neurosensory functions. PMID: 24068974
    2. The results in this study delimit the novel function of Ktub in Rh1 endocytosis and retinal degeneration PMID: 23228091
    3. TULP is principally expressed in the embryonic central and peripheral nervous systems. PMID: 12204260
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus. Cell projection, cilium membrane; Peripheral membrane protein.
  • 蛋白家族：
    TUB family
  • 組織特異性：
    Detected in sensory neurons which have a ciliary structure such as the chordotonal neurons, Orco-expressing olfactory receptor neurons, labellar gustatory receptor neurons and in the femoral chordotonal organ (at protein level). In the chordotonal neurons
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG9398

    STRING: 7227.FBpp0088961

    UniGene: Dm.3934