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  4. Recombinant Epstein-Barr virus Protein BNLF2a (BNLF2a), partial

Recombinant Epstein-Barr virus Protein BNLF2a (BNLF2a), partial

  • 中文名稱：
    Recombinant Epstein-Barr virus Protein BNLF2a (BNLF2a) ,partial,Yeast
  • 貨號(hào)：
    CSB-YP313737EFA1
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Epstein-Barr virus Protein BNLF2a (BNLF2a) ,partial,Yeast
  • 貨號(hào)：
    CSB-EP313737EFA1
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Epstein-Barr virus Protein BNLF2a (BNLF2a) ,partial,Yeast
  • 貨號(hào)：
    CSB-EP313737EFA1-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Epstein-Barr virus Protein BNLF2a (BNLF2a) ,partial,Yeast
  • 貨號(hào)：
    CSB-BP313737EFA1
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Epstein-Barr virus Protein BNLF2a (BNLF2a) ,partial,Yeast
  • 貨號(hào)：
    CSB-MP313737EFA1
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    BNLF2a
  • Uniprot No.：
  • 別名：
    BNLF2a; Protein BNLF2a
  • 種屬：
    Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Participates in viral evasion from HLA class I-restricted T-cell immunity. Associates with host TAP1 and TAP2 and prevents TAP-mediated peptide transport and subsequent loading.
  • 基因功能參考文獻(xiàn)：
    1. BNLF2a provides immune evasion properties to infected cells through inhibition of transporter associated with antigen processing (TAP)-transport of antigen peptides. BNLF2a is expressed in nearly half of EBV-associated gastric carcinomas. analyzed. PMID: 26178981
    2. N-terminal amino acid residues influence immune-evasive properties of BNLF2a. PMID: 22013037
    3. To optimally accomplish immune evasion, BNLF2a is composed of two specialized domains: its C-terminal tail anchor ensures membrane integration and endoplasmic reticulum retention, whereas its cytosolic N- terminus accomplishes inhibition of TAP function. PMID: 21296983
    4. during productive EBV infection, BNLF2a contributes to TAP inhibition and surface HLA class I down-regulation PMID: 19201886
  • 亞細(xì)胞定位：
    Host endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族：
    Lymphocryptovirus BNLF2a family
  • 數(shù)據(jù)庫鏈接：

    KEGG: vg:3783720