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  4. Recombinant Human ATP synthase F (0) complex subunit B1, mitochondrial (ATP5PB)

Recombinant Human ATP synthase F (0) complex subunit B1, mitochondrial (ATP5PB)

  • 中文名稱：
    Recombinant Human ATP synthase F(0) complex subunit B1, mitochondrial(ATP5PB),Yeast
  • 貨號：
    CSB-YP002358HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human ATP synthase F(0) complex subunit B1, mitochondrial(ATP5PB),Yeast
  • 貨號：
    CSB-EP002358HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human ATP synthase F(0) complex subunit B1, mitochondrial(ATP5PB),Yeast
  • 貨號：
    CSB-BP002358HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human ATP synthase F(0) complex subunit B1, mitochondrial(ATP5PB),Yeast
  • 貨號：
    CSB-MP002358HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    AT5F1_HUMAN; ATP synthase B chain mitochondrial; ATP synthase subunit b; ATP synthase subunit b mitochondrial; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit b,; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit b; isoform 1; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit B1; ATP5F1; ATPase subunit b; Cell proliferation inducing protein 47; H+ ATP synthase subunit b; MGC24431; mitochondrial; PIG47
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    43-256
  • 氨基酸序列
    PVPPLPEY GGKVRYGLIP EEFFQFLYPK TGVTGPYVLG TGLILYALSK EIYVISAETF TALSVLGVMV YGIKKYGPFV ADFADKLNEQ KLAQLEEAKQ ASIQHIQNAI DTEKSQQALV QKRHYLFDVQ RNNIAMALEV TYRERLYRVY KEVKNRLDYH ISVQNMMRRK EQEHMINWVE KHVVQSISTQ QEKETIAKCI ADLKLLAKKA QAQPVM
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
  • 基因功能參考文獻：
    1. Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance. PMID: 20038517
    2. Nitration of tyrosine residues 368 and 345 in the beta-subunit elicits FoF1-ATPase activity loss. PMID: 19650768
  • 亞細胞定位：
    Mitochondrion. Mitochondrion inner membrane.
  • 蛋白家族：
    Eukaryotic ATPase B chain family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 840

    OMIM: 603270

    KEGG: hsa:515

    STRING: 9606.ENSP00000358737

    UniGene: Hs.514870