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  4. Recombinant Human Anoctamin-7 (ANO7), partial

Recombinant Human Anoctamin-7 (ANO7), partial

  • 中文名稱：
    Recombinant Human Anoctamin-7(ANO7) ,partial,Yeast
  • 貨號：
    CSB-YP743597HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Anoctamin-7(ANO7) ,partial,Yeast
  • 貨號：
    CSB-EP743597HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Anoctamin-7(ANO7) ,partial,Yeast
  • 貨號：
    CSB-EP743597HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Anoctamin-7(ANO7) ,partial,Yeast
  • 貨號：
    CSB-BP743597HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Anoctamin-7(ANO7) ,partial,Yeast
  • 貨號：
    CSB-MP743597HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ANO7
  • Uniprot No.：
  • 別名：
    Ano7; ANO7_HUMAN; Anoctamin 7; Anoctamin-7; D TMPP; D-TMPP; Dresden transmembrane protein of the prostate; DTMPP; IPCA 5; IPCA-5; IPCA5; New gene expressed in prostate; NGEP; PCANAP5; PCANAP5L; Prostate cancer associated protein 5; Prostate cancer-associated protein 5; TMEM16G; Transmembrane protein 16G
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide. Does not exhibit calcium-activated chloride channel (CaCC) activity. May play a role in cell-cell interactions.
  • 基因功能參考文獻：
    1. high level of NGEP expression could be associated with good prognosis in prostate cancer PMID: 25808443
    2. NGEP protein is widely expressed in low-grade to high-grade prostate adenocarcinomas as well as benign prostate tissues, and the intensity of expression is inversely proportional to the level of malignancy. PMID: 23955683
    3. expressed only in prostate and prostate camcer is a promising target for the antibody-based therapies of prostate cancer PMID: 14981236
    4. Complete coding sequence of TMEM16G cDNA was determined by assembling 25 exons of TMEM16G gene PMID: 15375614
    5. description of the novel prostate-restricted molecule D-TMPP widely expressed in prostate cancer tissues PMID: 15761874
    6. NGEP is a glycoprotein with predicted glycosylation sites at N809 and N824. When these residues were converted to glutamine, glycosylation was abolished, confirming that the residues are extracellular PMID: 18676855
    7. NGEP is a potential target for T cell-mediated immunotherapy of prostate cancer. PMID: 19495750

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  • 亞細胞定位：
    [Isoform 1]: Cell membrane; Multi-pass membrane protein. Cell junction. Endoplasmic reticulum.; [Isoform 2]: Cytoplasm, cytosol.
  • 蛋白家族：
    Anoctamin family
  • 組織特異性：
    Specifically expressed in epithelial cells of the prostate (at protein level).
  • 數(shù)據(jù)庫鏈接：

    HGNC: 31677

    OMIM: 605096

    KEGG: hsa:50636

    STRING: 9606.ENSP00000274979

    UniGene: Hs.163909