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  4. Recombinant Human Carnitine O-palmitoyltransferase 1, brain isoform (CPT1C), partial

Recombinant Human Carnitine O-palmitoyltransferase 1, brain isoform (CPT1C), partial

  • 中文名稱：
    Recombinant Human Carnitine O-palmitoyltransferase 1, brain isoform(CPT1C) ,partial,Yeast
  • 貨號：
    CSB-YP855048HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Carnitine O-palmitoyltransferase 1, brain isoform(CPT1C) ,partial,Yeast
  • 貨號：
    CSB-EP855048HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Carnitine O-palmitoyltransferase 1, brain isoform(CPT1C) ,partial,Yeast
  • 貨號：
    CSB-EP855048HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Carnitine O-palmitoyltransferase 1, brain isoform(CPT1C) ,partial,Yeast
  • 貨號：
    CSB-BP855048HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Carnitine O-palmitoyltransferase 1, brain isoform(CPT1C) ,partial,Yeast
  • 貨號：
    CSB-MP855048HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    brain isoform; Carnitine acyltransferase like protein 1; Carnitine acyltransferase like protein1; Carnitine O palmitoyltransferase 1 brain isoform; Carnitine O palmitoyltransferase I; brain isoform; Carnitine O-palmitoyltransferase 1; Carnitine O-palmitoyltransferase I; Carnitine palmitoyltransferase 1; brain; Carnitine palmitoyltransferase 1C; Carnitine palmitoyltransferase I related C; Carnitine palmitoyltransferase1C; CAT L1; CATL 1; CATL1; CPT 1 like pseudogene; Cpt 1c; CPT 1P; CPT I C; CPT IC; Cpt1 c; CPT1 like pseudogene; CPT1-B; Cpt1c; CPT1C_HUMAN; CPT1P; CPTI-B; CPTIC
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    May play a role in lipid metabolic process.
  • 基因功能參考文獻：
    1. Depletion of PPARalpha resulted in low CPT1C expression. PMID: 28334197
    2. CPT1C binds malonyl-CoA and long-chain acyl-CoA suggest that it is a sensor of lipid metabolism in neurons, where it appears to impact ceramide and triacylglycerol metabolism. [review] PMID: 26708865
    3. CPT1c is found in brain regions that are related to food intake and neuropsychiatric disease. CPT1c affects ceramide levels, endocannabionoids, and oxidative processes and may play an important role in various brain functions such as learning. PMID: 26041663
    4. CPT1C mutation associated with novel form of pure autosomal dominant hereditary spastic paraplegia. PMID: 25751282
    5. High grade glioblastoma is associated with increased level of ZFP57, a protein involved in gene imprinting, and aberrant expression of CPT1A and CPT1C. PMID: 24618825
    6. Data suggest that an involvement of CPT1C in cellular energy-sensing pathways and provide evidence for a role of CPT1C in hypothalamic regulation of energy homeostasis. PMID: 21961029
    7. cells can use a novel mechanism involving CPT1C and fatty acid metabolism to protect against metabolic stress PMID: 21576264
    8. CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity PMID: 18192268
    9. Accumulation of 3-hydroxylated intermediates of long-chain fatty acids may contribute to the pathogenesis of retinopathy in MTP deficiencies. PMID: 18385088

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  • 相關(guān)疾?。?/div>
    Spastic paraplegia 73, autosomal dominant (SPG73)
  • 亞細胞定位：
    Mitochondrion outer membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite. Cell projection, axon. Endoplasmic reticulum.
  • 蛋白家族：
    Carnitine/choline acetyltransferase family
  • 組織特異性：
    Expressed predominantly in brain and testis. Expressed in motor neurons.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18540

    OMIM: 608846

    KEGG: hsa:126129

    STRING: 9606.ENSP00000319343

    UniGene: Hs.112195