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  4. Recombinant Human Coiled-coil domain-containing protein 80 (CCDC80), partial

Recombinant Human Coiled-coil domain-containing protein 80 (CCDC80), partial

  • 中文名稱：
    Recombinant Human Coiled-coil domain-containing protein 80(CCDC80) ,partial,Yeast
  • 貨號：
    CSB-YP741736HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Coiled-coil domain-containing protein 80(CCDC80) ,partial,Yeast
  • 貨號：
    CSB-EP741736HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Coiled-coil domain-containing protein 80(CCDC80) ,partial,Yeast
  • 貨號：
    CSB-EP741736HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Coiled-coil domain-containing protein 80(CCDC80) ,partial,Yeast
  • 貨號：
    CSB-BP741736HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Coiled-coil domain-containing protein 80(CCDC80) ,partial,Yeast
  • 貨號：
    CSB-MP741736HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CCDC80
  • Uniprot No.：
  • 別名：
    2610001E17Rik; CCD50; CCD80_HUMAN; CCDC80; CL2; Coiled coil domain containing 80; Coiled coil domain containing protein 50; Coiled-coil domain-containing protein 80; Down regulated by oncogenes protein 1; Down-regulated by oncogenes protein 1; DRO1; MGC131805; MGC134851; Nuclear envelope protein okuribin; okuribin; OTTMUSP00000030743; Protein Ymer; SSG1; steroid sensitive gene 1; steroid sensitive protein 1; Up-regulated in BRS-3 deficient mouse homolog; URB
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Promotes cell adhesion and matrix assembly.
  • 基因功能參考文獻：
    1. Ccdc80 is a novel betacat-regulated gene in adrenocortical cells PMID: 25029241
    2. activation of PKGI with cGMP regulated SSG1 intracellular distribution. PMID: 23831687
    3. Data suggest that CCDC80 expression is down-regulated in many thyroid carcinomas; loss of heterozygosity partially accounts for CCDC80 down-regulation in thyroid carcinoma; CCDC80 expression positively regulates expression of E-cadherin. PMID: 23666966
    4. The CCDC80 protein has three P-DUDES structural domains. These domains have significant albeit remote sequence similarity to thioredoxin-like domains and are predicted to have an oxidoreductase function. PMID: 209648
    5. Results reveal DRO1 as an AIB1-targeted tumor suppressor, providing a novel mechanism for AIB1-dependent inhibition of apoptosis. PMID: 21871888
    6. Downregulated during osteoblastic differentiation of bone marrow stromal cells. Suggests role in skeletogenesis. PMID: 15325258
    7. URB is expressed in human dermal papilla cells PMID: 15998583
    8. In conclusion, the expression pattern of URB suggests its role in obesity and the results suggest that URB is secreted, at least in part, from adipocytes. PMID: 18178152

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  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    CCDC80 family
  • 組織特異性：
    Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30649

    OMIM: 608298

    KEGG: hsa:151887

    STRING: 9606.ENSP00000206423

    UniGene: Hs.477128