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Recombinant Human Humanin-like 1 (MTRNR2L1)

  • 中文名稱(chēng)：
    人MTRNR2L1重組蛋白
  • 貨號(hào)：
    CSB-YP317683HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    人MTRNR2L1重組蛋白
  • 貨號(hào)：
    CSB-EP317683HU
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    人MTRNR2L1重組蛋白
  • 貨號(hào)：
    CSB-EP317683HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    人MTRNR2L1重組蛋白
  • 貨號(hào)：
    CSB-BP317683HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    人MTRNR2L1重組蛋白
  • 貨號(hào)：
    CSB-MP317683HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    MTRNR2L1
  • Uniprot No.：
  • 別名：
    MTRNR2L1; Humanin-like 1; HN1; MT-RNR2-like protein 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-24
  • 氨基酸序列
    MAPRGFSCLL LSTSEIDLPV KRRT
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Plays a role as a neuroprotective and antiapoptotic factor.
  • 基因功能參考文獻(xiàn)：
    1. Humanin (HN) and glucose transporter 8 (GLUT8) in pregnancies complicated by intrauterine growth restriction PMID: 29590129
    2. Humanin protected RPE cells against oxidative stress-induced cell death and restored mitochondrial function. PMID: 26990160
    3. Humanin Peptide Binds to Insulin-Like Growth Factor-Binding Protein 3 (IGFBP3) and Regulates Its Interaction with Importin-beta. PMID: 26216267
    4. Data suggest that humanin (the first small peptide of a putative set of mitochondrial derived peptides) exhibits strong cytoprotective actions against various stress and disease models. PMID: 23402768
    5. findings implied that HN protects cortical neurons from I/R injury by the increased SOD activity and that the protective effect of HN on neurons against I/R is concentration-dependent PMID: 21935731
    6. The in vivo studies suggest that humanin may protect against cognitive impairment, also due to ischemia/reperfusion injury.[review] PMID: 22010475
    7. Immunolocalization of humanin in human sperm and testis. PMID: 20542501

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  • 亞細(xì)胞定位：
    Secreted. Cytoplasm.
  • 蛋白家族：
    Humanin family
  • 組織特異性：
    Highly expressed in the kidney, heart muscle and testis.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 37155

    OMIM: 616985

    KEGG: hsa:100462977

    STRING: 9606.ENSP00000439228

    UniGene: Hs.740185