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  4. Recombinant Human Keratin-associated protein 5-1 (KRTAP5-1)

Recombinant Human Keratin-associated protein 5-1 (KRTAP5-1)

  • 中文名稱：
    人KRTAP5-1重組蛋白
  • 貨號(hào)：
    CSB-YP757208HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    人KRTAP5-1重組蛋白
  • 貨號(hào)：
    CSB-EP757208HU
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    人KRTAP5-1重組蛋白
  • 貨號(hào)：
    CSB-EP757208HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人KRTAP5-1重組蛋白
  • 貨號(hào)：
    CSB-BP757208HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人KRTAP5-1重組蛋白
  • 貨號(hào)：
    CSB-MP757208HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    KRTAP5-1
  • Uniprot No.：
  • 別名：
    KRTAP5-1; KAP5.1; KRN1L; KRTAP5.1; Keratin-associated protein 5-1; Keratin; cuticle; ultrahigh sulphur 1-like; Keratin-associated protein 5.1; Ultrahigh sulfur keratin-associated protein 5.1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-278
  • 氨基酸序列
    MGCCGCSGGC GSSCGGCGSG CGGCGSGCGG CGSGCGGSGS SCCVPVCCCK PVCCRVPTCS CSSCGKGGCG SSGGSKGGCG SCGGCKGGCG SCGGSKGGCG SCGGSKGGCG SCGGSKGGCG SGCGGCGSSC CVPVCCCKPM CCCVPACSCS SCGKGGCGSC GCSKGACGSC GGSKGGCGSC GGCKGGCGSC GGSKGGCGSG CGGCGSGCGV PVCCCSCSSC GSCAGSKGGC GSSCSQCSCC KPCCCSSGCG SSCCQSSCCK PCCSQSSCCV PVCCQCKI
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
  • 基因功能參考文獻(xiàn)：
    1. A novel mutation designated as E477K of K1 was identified in epidermolytic hyperkeratosis. PMID: 12234709
    2. KAP5 gene expression in human hair follicles is regulated by Runx1 PMID: 16442267
  • 蛋白家族：
    KRTAP type 5 family
  • 組織特異性：
    Expressed in hair root but not in skin. Expressed also in lung, pancreas, ovary, testis.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 23596

    OMIM: 148022

    KEGG: hsa:387264

    STRING: 9606.ENSP00000371606

    UniGene: Hs.632147