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Recombinant Human Kita-kyushu lung cancer antigen 1 (CT83)

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  • 中文名稱：
    Recombinant Human Kita-kyushu lung cancer antigen 1(CT83)
  • 貨號：
    CSB-EP711093HU
  • 規(guī)格：
    ￥1536
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP711093HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) CT83.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP711093HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) CT83.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    CT83
  • Uniprot No.：
  • 別名：
    CT83; CXorf61; KKLC1; Kita-kyushu lung cancer antigen 1; KK-LC-1; Cancer/testis antigen 83
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length
  • 來源：
    E.coli
  • 分子量：
    26.8kDa
  • 表達區(qū)域：
    1-113aa
  • 氨基酸序列
    MNFYLLLASSILCALIVFWKYRRFQRNTGEMSSNSTALALVRPSSSGLINSNTDNNLAVYDLSRDILNNFPHSIARQKRILVNLSMVENKLVELEHTLLSKGFRGASPHRKST
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白標簽：
    N-terminal 6xHis-B2M-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Tris-based buffer,50% glycerol
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 基因功能參考文獻：
    1. High KK-LC-1 expression was detected in breast cancer, especially in oestrogen receptor-negative subtypes. PMID: 30275220
    2. The KK-LC-1 expression rate was high even in patients with stage I cancer, suggesting that KK-LC-1 is a useful biomarker for early diagnosis of gastric cancer. PMID: 29290656
    3. KK-LC-1 was frequently expressed in gastric cancer caused by H. pylori infection. PMID: 28438869
    4. CXorf61 is a target for T cell based immunotherapy of triple-negative breast cancer. PMID: 26327325
    5. The frequency of KK-LC-1 expression was higher than that of the other CTAs. KK-LC-1 might be a useful target for immunotherapy and in diagnosis of gastric cancer. PMID: 26026129

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  • 亞細胞定位：
    Cell membrane; Single-pass type II membrane protein.
  • 組織特異性：
    Specifically expressed in testis. Expressed by cancer cell lines.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 33494

    OMIM: 300625

    KEGG: hsa:203413

    STRING: 9606.ENSP00000360961

    UniGene: Hs.97892