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  4. Recombinant Human Lon protease homolog 2, peroxisomal (LONP2), partial

Recombinant Human Lon protease homolog 2, peroxisomal (LONP2), partial

  • 中文名稱：
    人LONP2重組蛋白
  • 貨號：
    CSB-YP803134HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人LONP2重組蛋白
  • 貨號：
    CSB-EP803134HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人LONP2重組蛋白
  • 貨號：
    CSB-EP803134HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人LONP2重組蛋白
  • 貨號：
    CSB-BP803134HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人LONP2重組蛋白
  • 貨號：
    CSB-MP803134HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    LONP2
  • Uniprot No.：
  • 別名：
    Lon peptidase 2, peroxisomal; Lon protease 2; Lon protease homolog 2; Lon protease homolog 2 peroxisomal; Lon protease like protein 2; Lon protease-like protein 2; LONP; lonp2; LONP2_HUMAN; LONPL; MGC4840; peroxisomal; Peroxisomal Lon protease; Peroxisomal Lon protease homolog 2; Peroxisomal LON protease like
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

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靶點詳情

  • 功能：
    ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.
  • 基因功能參考文獻：
    1. Findings suggest that LONP2 promotes cervical tumorigenesis via oxidative stress. PMID: 29502128
    2. The proteolytic activity of oligomeric Tysnd1 is in turn controlled by self-cleavage of Tysnd1 and degradation of Tysnd1 cleavage products by PsLon. PMID: 22002062
    3. Lon recognizes specific surface determinants or folds, initiates proteolysis at solvent-accessible sites of MPPalpha and StAR, and generates unfolded polypeptides that are then processively degraded PMID: 15870080
  • 亞細胞定位：
    Peroxisome matrix.
  • 蛋白家族：
    Peptidase S16 family
  • 組織特異性：
    Widely expressed, with high levels in the liver, kidney and pancreas.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20598

    OMIM: 617774

    KEGG: hsa:83752

    STRING: 9606.ENSP00000285737

    UniGene: Hs.295923