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  4. Recombinant Human Myosin-binding protein C, fast-type (MYBPC2), partial

Recombinant Human Myosin-binding protein C, fast-type (MYBPC2), partial

  • 中文名稱：
    人MYBPC2重組蛋白
  • 貨號：
    CSB-BP618884HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人MYBPC2重組蛋白
  • 貨號：
    CSB-EP618884HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人MYBPC2重組蛋白
  • 貨號：
    CSB-MP618884HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    Name:MYBPC2 Synonyms:MYBPCF
  • Uniprot No.：
  • 別名：
    C protein, skeletal muscle fast isoform; C-protein; Fast MyBP C; Fast MyBP-C; MGC163408; MYBPC; Mybpc2; MYBPCF; Myosin binding protein C, fast type; Myosin-binding protein C, fast-type; MYPC2_HUMAN; skeletal muscle fast isoform
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
  • 基因功能參考文獻：
    1. the mean methylation level of CpGs was significantly higher in MYBPC3 than MYBPC2. PMID: 20740642
    2. The patients with a frameshift deletion mutation of MyBPC may develop LV systolic dysfunction and suffer from cardiovascular events through mid-life and beyond. PMID: 20605413
    3. Identification of interactions between domains of Myosin binding protein-C that are modulated by hypertrophic cardiomyopathy missense mutations. PMID: 12386147
    4. the CD-loop is a natively unfolded sequence with a likely coupling between folding and ligand binding. PMID: 17876814
    5. Role and quaternary structure of MyBPC in skeletal muscle. PMID: 18201573
    6. The distribution of MyBP-C in the A-bands of cardiac and skeletal muscles and compare this to the A-band structure in cardiac muscle of MyBP-C-deficient mice, was investigated. PMID: 18817784

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  • 蛋白家族：
    Immunoglobulin superfamily, MyBP family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 7550

    OMIM: 160793

    KEGG: hsa:4606

    STRING: 9606.ENSP00000350332

    UniGene: Hs.85937