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  4. Recombinant Human Pre-B lymphocyte protein 3 (VPREB3)

Recombinant Human Pre-B lymphocyte protein 3 (VPREB3)

  • 中文名稱：
    人VPREB3重組蛋白
  • 貨號：
    CSB-YP891724HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人VPREB3重組蛋白
  • 貨號：
    CSB-EP891724HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人VPREB3重組蛋白
  • 貨號：
    CSB-EP891724HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人VPREB3重組蛋白
  • 貨號：
    CSB-BP891724HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人VPREB3重組蛋白
  • 貨號：
    CSB-MP891724HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    VPREB3
  • Uniprot No.：
  • 別名：
    N27C7 2; N27C7-2; Pre B lymphocyte protein 3; Pre-B lymphocyte protein 3; PRO619; Protein VPreB3; UNQ355; VPRE3_HUMAN; VPREB3; VpreB3 protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    21-123
  • 氨基酸序列
    VLAQLDALLV FPGQVAQLSC TLSPQHVTIR DYGVSWYQQR AGSAPRYLLY YRSEEDHHRP ADIPDRFSAA KDEAHNACVL TISPVQPEDD ADYYCSVGYG FSP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells.
  • 基因功能參考文獻：
    1. A possible role for VPREB3 in aldosterone biosynthesis. PMID: 25861052
    2. levels of VPREB3 mRNA in aldosterone-producing adenomas directly correlate to plasma aldosterone concentrations in peripheral blood of respective patients PMID: 25861052
    3. mouse VpreB3 associates with mu heavy chains early in pre-B cell receptor biosynthesis PMID: 8491176
    4. VpreB3 may play a role in the regulation of the maturation and secretion of free IgLC in chicken B cells PMID: 14670953
    5. the combined immunohistochemical detection of VPREB3 and ID3 is applicable to the routine diagnostic in case of mature aggressive B-cell lymphomas. PMID: 24493312
    6. Data show that the absence of VpreB3 is virtually always associated with wild-type c-MYC alleles. PMID: 20823132
    7. the present study confirms the co-existence of surrogate lambda and kappa receptors that are proposed to work in concert to promote B lymphocyte maturation. PMID: 15757909

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  • 蛋白家族：
    Immunoglobulin superfamily
  • 組織特異性：
    Expressed in B-cell precursors. Expressed in fetal liver, bone marrow, spleen and lymph node.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 12710

    OMIM: 605017

    KEGG: hsa:29802

    STRING: 9606.ENSP00000248948

    UniGene: Hs.136713