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  4. Recombinant Human Pro-FMRFamide-related neuropeptide FF (NPFF), partial

Recombinant Human Pro-FMRFamide-related neuropeptide FF (NPFF), partial

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  • 中文名稱：
    人NPFF重組蛋白
  • 貨號：
    CSB-EP015981HU
  • 規(guī)格：
    ￥1836
  • 促銷：
    現(xiàn)貨重組蛋白特價促銷
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    NPFF
  • Uniprot No.：
  • 別名：
    FMRFamide-related peptides
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 來源：
    E.coli
  • 分子量：
    32.8 kDa
  • 表達區(qū)域：
    66-76aa
  • 氨基酸序列
    SQAFLFQPQRF
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白標簽：
    N-terminal GST-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels.
  • 基因功能參考文獻：
    1. Our results...highlight the neuropeptide FF-amide peptide encoding gene (NPFF) as a novel candidate risk gene for both migraine with aura and migraine without aura PMID: 26660531
    2. reduction of NPFF release within the dorsal motor nucleus and ambiguus nucleus could serve as a possible cause of the impairment of cardiac vagal control in hypertensive patients PMID: 21120930
    3. expression of hNPFF2 receptor mRNA was up-regulated by neuropeptide FF PMID: 16336216
    4. neuropeptide FF and micro-opioid receptor association could be a possible molecular basis for anti-opioid activity PMID: 17224450
    5. the findings from the early studies on the analgesic and morphine modulating activities suggested a role for NPFF in pain modulation--review PMID: 17854890

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    FARP (FMRFamide related peptide) family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 7901

    OMIM: 604643

    KEGG: hsa:8620

    STRING: 9606.ENSP00000267017

    UniGene: Hs.733076