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Recombinant Human Talanin (ZNF365)

  • 中文名稱：
    人ZNF365重組蛋白
  • 貨號：
    CSB-YP754628HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人ZNF365重組蛋白
  • 貨號：
    CSB-EP754628HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人ZNF365重組蛋白
  • 貨號：
    CSB-EP754628HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人ZNF365重組蛋白
  • 貨號：
    CSB-BP754628HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人ZNF365重組蛋白
  • 貨號：
    CSB-MP754628HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ZNF365
  • Uniprot No.：
  • 別名：
    ZNF365; KIAA0844; Talanin
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-216
  • 氨基酸序列
    MSALGQITIT VSRCWNTERN QTDKNPCLHG AYLQLRETVK NKSTHLKKPL MKQAPPWKDH LTFQPLHPAE RKTQVWRWQS GNSSDLETTS SASPWPTGSN RDVVLNTLAE SCCGLSELIT APPYAGVSIQ GFSQIWVLFP FCGGTFHHNE KDVLGLQDFE RESVSTSQSR NISLLTLGQL QNCVIGKLTI IDLLTEHLLG VRHGVICFPW GLPSSS
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    May play a role in uric acid excretion.
  • 基因功能參考文獻(xiàn)：
    1. It regulates cortical cell positioning and neurite extension by sustaining the anterograde transport of Lis1/DISC1 through control of Ndel1 phosphorylation PMID: 27333658
    2. The SNP rs10995251 in ZNF365 gene is associated with the susceptibility to bronchial asthma in children. PMID: 26287344
    3. we discuss the expression of DISC1, DBZ, and SGK1 , their roles in the regulation of oligodendrocyte function, possible interactions of DISC1 and DBZ in relation to SZ, and the activation of the SGK1 signaling cascade in relation to MDD. PMID: 25705664
    4. We evaluated the association of polymorphisms of ZNF365 gene with the metabolic disorders in children with urolithiasis PMID: 25060549
    5. Single-nucleotide polymorphism in ZNF365 gene is associated with Crohn's disease. PMID: 25489960
    6. In the absence of ZNF365, defective telomeres engage in aberrant recombination of telomere ends, leading to increased telomere sister chromatid exchange and formation of anaphase DNA bridges, including ultra-fine DNA bridges, and ultimately increased cytokinesis failure and aneuploidy PMID: 23776040
    7. These results suggest an homologous recombination repair-dependent function of ZNF365 in preventing genomic instability. PMID: 23966166
    8. Our findings suggest that RAB3GAP1 and ZNF365 are relevant candidate genes for SCD and will contribute to the mechanistic understanding of SCD susceptibility. PMID: 23593153
    9. Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. PMID: 22351618
    10. the non-synonymous Ala62Thr SNP, rs7076156, underlies the association between 10q21 and CD risk and suggest that this SNP acts by altering expression of genes under the control of ZNF365 isoform D. PMID: 21257989
    11. The association of PCNT2 and DBZ with schizophrenia and bipolar disorder in a case-control study of Japanese cohorts, was examined. PMID: 19191256
    12. A novel gene responsible for UAN was identified in an Italian population. PMID: 12740763
    13. findings indicate that Su48 can form a protein complex with Nde1 in the centrosome and plays an important role for successful mitosis PMID: 16682949

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  • 相關(guān)疾?。?/div>
    Uric acid nephrolithiasis (UAN)
  • 組織特異性：
    Isoform 4 is expressed in placenta, lung, kidney and pancreas.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18194

    OMIM: 605990

    STRING: 9606.ENSP00000387091

    UniGene: Hs.22653