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  4. Recombinant Human Transcription initiation factor TFIID subunit 5 (TAF5)

Recombinant Human Transcription initiation factor TFIID subunit 5 (TAF5)

  • 中文名稱：
    人TAF5重組蛋白
  • 貨號：
    CSB-YP613596HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人TAF5重組蛋白
  • 貨號：
    CSB-EP613596HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人TAF5重組蛋白
  • 貨號：
    CSB-EP613596HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人TAF5重組蛋白
  • 貨號：
    CSB-BP613596HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人TAF5重組蛋白
  • 貨號：
    CSB-MP613596HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品評價

靶點詳情

  • 功能：
    TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. TAF5/TAFII100 interacts strongly with the histone H4-related TAF6/TAFII80 and the histone H3-related TAF9/TAFII31, as well as a stable complex comprised of both TAF5/TAFII80 and TAF6/TAFII31. Apparently weaker interactions of TAF5/TAFII100 with TBP, TAF1/TAFII250, TAF11/TAFII28, and TAF12/TAFII20, but not TAF7/TAFII55, also have been observed.
  • 基因功能參考文獻：
    1. TFIID TAF6-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 and is modulated by TAF5 protein. PMID: 22696218
    2. reversible SUMO modification at hsTAF5 contributes to the dynamic regulation of TFIID promoter-binding activity in human cells PMID: 15637059
    3. TAF5 protein demonstrates the ability of the N-terminal half of the TAF5 gene to form a flexible, extended dimer, a key property required for the assembly of the TFIID complex PMID: 17227857
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    WD repeat TAF5 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11539

    OMIM: 601787

    KEGG: hsa:6877

    STRING: 9606.ENSP00000358854

    UniGene: Hs.96103