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  4. Recombinant Human UDP-xylose and UDP-N-acetylglucosamine transporter (SLC35B4), partial

Recombinant Human UDP-xylose and UDP-N-acetylglucosamine transporter (SLC35B4), partial

  • 中文名稱：
    人SLC35B4重組蛋白
  • 貨號(hào)：
    CSB-YP853373HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    人SLC35B4重組蛋白
  • 貨號(hào)：
    CSB-EP853373HU
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    人SLC35B4重組蛋白
  • 貨號(hào)：
    CSB-EP853373HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SLC35B4重組蛋白
  • 貨號(hào)：
    CSB-BP853373HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SLC35B4重組蛋白
  • 貨號(hào)：
    CSB-MP853373HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SLC35B4
  • Uniprot No.：
  • 別名：
    SLC35B4; YEA4; PSEC0055; UDP-xylose and UDP-N-acetylglucosamine transporter; Solute carrier family 35 member B4; YEA4 homolog
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi.
  • 基因功能參考文獻(xiàn)：
    1. Glucose levels activate SLC35B4 expression. This triggers a downstream effect via Hsp60 and other proteins. We hypothesize that the downstream effect on the proteins is mediated via altering the glycosylation pattern inside liver cells PMID: 29867058
    2. subcellular localization of SLC35B4 PMID: 21918738
    3. Decreased SLC35B4 expression led to increased gluconeogenesis in HepG2 cells. PMID: 21507882
    4. Transport capabilities for UDP-Glc and UDP-Xyl were determined with Golgi vesicles isolated from transformed cells PMID: 15911612
  • 亞細(xì)胞定位：
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Nucleotide-sugar transporter family, SLC35B subfamily
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 20584

    OMIM: 610923

    KEGG: hsa:84912

    STRING: 9606.ENSP00000367770

    UniGene: Hs.490181