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  4. Recombinant Human Zinc finger and BTB domain-containing protein 46 (ZBTB46)

Recombinant Human Zinc finger and BTB domain-containing protein 46 (ZBTB46)

  • 中文名稱：
    人ZBTB46重組蛋白
  • 貨號(hào)：
    CSB-YP803124HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人ZBTB46重組蛋白
  • 貨號(hào)：
    CSB-EP803124HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人ZBTB46重組蛋白
  • 貨號(hào)：
    CSB-EP803124HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人ZBTB46重組蛋白
  • 貨號(hào)：
    CSB-BP803124HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人ZBTB46重組蛋白
  • 貨號(hào)：
    CSB-MP803124HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ZBTB46
  • Uniprot No.：
  • 別名：
    ZBTB46; BTBD4; ZNF340; Zinc finger and BTB domain-containing protein 46; BTB-ZF protein expressed in effector lymphocytes; BZEL; BTB/POZ domain-containing protein 4; Zinc finger protein 340
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-589
  • 氨基酸序列
    MNNRKEDMEI TSHYRHLLRE LNEQRQHGVL CDVCVVVEGK VFKAHKNVLL GSSRYFKTLY CQVQKTSEQA TVTHLDIVTA QGFKAIIDFM YSAHLALTSR NVIEVMSAAS FLQMTDIVQA CHDFIKAALD ISIKSDASDE LAEFEIGASS SSSTEALISA VMAGRSISPW LARRTSPANS SGDSAIASCH DGGSSYGKED QEPKADGPDD VSSQPLWPGD VGYGPLRIKE EQVSPSQYGG SELPSAKDGA VQNSFSEQSA GDAWQPTGRR KNRKNKETVR HITQQVEDDS RASSPVPSFL PTSGWPFSSR DSNADLSVTE ASSSDSRGER AELYAQVEEG LLGGEASYLG PPLTPEKDDA LHQATAVANL RAALMSKNSL LSLKADVLGD DGSLLFEYLP RGAHSLSLNE FTVIRKKFKC PYCSFSAMHQ CILKRHMRSH TGERPYPCEI CGKKFTRREH MKRHTLVHSK DKKYVCKVCS RVFMSAASVG IRHGSRRHGV CTDCAGRGMA GPLDHGGGGG EGSPEALFPG DGPYLEDPED PRGEAEELGE DDEGLAPEDA LLADDKDEED SPRPRSPPGG PDKDFAWLS
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Functions as a transcriptional repressor for PRDM1.
  • 基因功能參考文獻(xiàn)：
    1. Authors report a novel tumor promoter, ZBTB46, which is negatively regulated by AR signaling via microRNA (miR)-1-mediated downregulation. ZBTB46 is associated with malignant prostate cancer and is essential for metastasis. PMID: 28692046
    2. A single nucleotide polymorphisn in ZBTB46, rs6062314, is associated with an increased genetic risk for multiple sclerosis. PMID: 23739915
  • 亞細(xì)胞定位：
    Nucleus.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 16094

    OMIM: 614639

    KEGG: hsa:140685

    STRING: 9606.ENSP00000245663

    UniGene: Hs.585028