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Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx (vpx)

  • 中文名稱：
    Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx(vpx),Yeast
  • 貨號：
    CSB-YP361672HLY
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx(vpx),Yeast
  • 貨號：
    CSB-EP361672HLY
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx(vpx),Yeast
  • 貨號：
    CSB-EP361672HLY-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx(vpx),Yeast
  • 貨號：
    CSB-BP361672HLY
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx(vpx),Yeast
  • 貨號：
    CSB-MP361672HLY
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    vpx
  • Uniprot No.：
  • 別名：
    vpxProtein Vpx; Viral protein X; X ORF protein
  • 種屬：
    Human immunodeficiency virus type 2 subtype A (isolate NIH-Z) (HIV-2)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-112
  • 氨基酸序列
    MTDPRETVPP GNSGEETIEE AFAWLDRTVE AINREAVNHH PRELIFQVWQ RSWRYWHDEQ GMSTSYTKYR YLCLIQMAMY MHAKRDGTCL GGGMGQKGGD QGPPPPPPPG LV
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription.
  • 亞細(xì)胞定位：
    Virion. Host nucleus.
  • 蛋白家族：
    Lentivirus VPX protein family