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  4. Recombinant Lymphocytic choriomeningitis virus RNA-directed RNA polymerase L (L), partial

Recombinant Lymphocytic choriomeningitis virus RNA-directed RNA polymerase L (L), partial

  • 中文名稱：
    Recombinant Lymphocytic choriomeningitis virus RNA-directed RNA polymerase L(L) ,partial,Yeast
  • 貨號：
    CSB-YP319669LKW
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Lymphocytic choriomeningitis virus RNA-directed RNA polymerase L(L) ,partial,Yeast
  • 貨號：
    CSB-EP319669LKW
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Lymphocytic choriomeningitis virus RNA-directed RNA polymerase L(L) ,partial,Yeast
  • 貨號：
    CSB-EP319669LKW-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Lymphocytic choriomeningitis virus RNA-directed RNA polymerase L(L) ,partial,Yeast
  • 貨號：
    CSB-BP319669LKW
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Lymphocytic choriomeningitis virus RNA-directed RNA polymerase L(L) ,partial,Yeast
  • 貨號：
    CSB-MP319669LKW
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    L
  • Uniprot No.：
  • 別名：
    L; Segment; L; RNA-directed RNA polymerase L; Protein L; EC 2.7.7.48; EC 3.1.-.-; Large structural protein; Replicase; Transcriptase
  • 種屬：
    Lymphocytic choriomeningitis virus (strain Armstrong) (LCMV)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    RNA-dependent RNA polymerase which is responsible for replication and transcription of the viral RNA genome. During transcription, synthesizes 4 subgenomic RNAs, and assures their capping by a cap-snatching mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription. The 3'-end of subgenomic mRNAs molecules are heterogeneous and not polyadenylated. The replicase function is to direct synthesis of antigenomic and genomic RNA which are encapsidated and non capped. As a consequence of the use of the same enzyme for both transcription and replication, these mechanisms need to be well coordinated. These processes may be regulated by proteins N and Z in a dose-dependent manner.
  • 基因功能參考文獻：
    1. Data suggest that L protein from LCMV interactions with host proteome, specifically DDX3X, NKRF, and TRIM21. (LCMV = Lymphocytic choriomeningitis mammarenavirus; DDX3X = DEAD-box helicase 3; NKRF = NF-kappa-B-repressing factor; TRIM21 = tripartite motif-containing protein-21) PMID: 29261807
    2. The GP precursor is 498 amino acids and L protein encodes the L polymerase of 2,209 amino acids. PMID: 18493846
  • 亞細胞定位：
    Virion. Host cytoplasm.
  • 蛋白家族：
    Arenaviridae RNA polymerase family
  • 數(shù)據(jù)庫鏈接：

    KEGG: vg:956589