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Recombinant Mouse Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 (Alkbh2)

  • 中文名稱：
    Recombinant Mouse Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2(Alkbh2),Yeast
  • 貨號：
    CSB-YP754198MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2(Alkbh2),Yeast
  • 貨號：
    CSB-EP754198MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2(Alkbh2),Yeast
  • 貨號：
    CSB-EP754198MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2(Alkbh2),Yeast
  • 貨號：
    CSB-BP754198MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2(Alkbh2),Yeast
  • 貨號：
    CSB-MP754198MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Alkbh2
  • Uniprot No.：
  • 別名：
    Alkbh2; Abh2DNA oxidative demethylase ALKBH2; EC 1.14.11.33; Alkylated DNA repair protein alkB homolog 2; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-239
  • 氨基酸序列
    MDKFLVRPDL RDLQGGGEEP APTGGASGDL KSPDWRHLRA EGLSCDYTVL FGKAEADKIF RELEQEVEYF TGALAKVQVF GKWHSVPRKQ ATYGDAGLTY TFSGLTLTPK PWVPVLERVR DRVCEVTGQT FNFVLVNRYK DGCDHIGEHR DDERELAPGS PIASVSFGAC RDFIFRHKDS RGKRPRRTVE VVRLQLAHGS LLMMNPPTNT HWYHSLPIRK RVLAPRVNLT FRKILPTKK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine. Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.
  • 基因功能參考文獻：
    1. Although both Alkbh2 and Alkbh3 can protect against methyl methanesulfonate-induced cell death, only Alkbh2 shows statistically significant protection against mutations following treatment with this exogenous methylating agent. PMID: 22429847
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    AlkB family
  • 組織特異性：
    Detected in liver, testis and kidney (at protein level). Detected in heart and testis.
  • 數(shù)據(jù)庫鏈接：