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Recombinant Mouse CREB3 regulatory factor (Crebrf)

  • 中文名稱：
    Recombinant Mouse CREB3 regulatory factor(Crebrf),Yeast
  • 貨號：
    CSB-YP804489MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse CREB3 regulatory factor(Crebrf),Yeast
  • 貨號：
    CSB-EP804489MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse CREB3 regulatory factor(Crebrf),Yeast
  • 貨號：
    CSB-EP804489MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse CREB3 regulatory factor(Crebrf),Yeast
  • 貨號：
    CSB-BP804489MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse CREB3 regulatory factor(Crebrf),Yeast
  • 貨號：
    CSB-MP804489MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Crebrf
  • Uniprot No.：
  • 別名：
    CrebrfCREB3 regulatory factor; Luman recruitment factor; LRF
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-640
  • 氨基酸序列
    MPQPSVSGMD PPFGDAFRSH TFSEQTLMST DLLANSSDPD FMYELDREMN YQQNPRDNFL SLEDCKDIEN LETFTDVLDN EDALTSNWEQ WDTYCEDLTK YTKLTSCDIW GTKEVDYLGL DDFSSPYQDE EVISKTPTLA QLNSEDSQSV SDSLYYPDSL FSVKQNPLPP SSFPSKKITN RAAAPVCSSK TLQAEVPSSD CVQKASKPTS STQIMVKTNM YHNEKVNFHV ECKDYVKKAK VKINPVQQGR PLLSQVHIDA AKENTCYCGA VAKRQERRGV EPHQGRGTPA LPFKETQELL LSPLTQDSPG LVATAESGSL SASTSVSDSS QKKEEHNYSL FVSDNMREQP TKYSPEDDED DEDEFDDEDH DEGFGSEHEL SENEEEEEEE EDYEDDRDDD ISDTFSEPGY ENDSVEDLKE MTSISSRKRG KRRYFWEYSE QLTPSQQERI LRPSEWNRDT LPSNMYQKNG LHHGKYAVKK SRRTDVEDLT PNPKKLLQIG NELRKLNKVI SDLTPVSELP LTARPRSRKE KNKLASRACR LKKKAQYEAN KVKLWGLNTE YDNLLFVINS IKQDIVNRVQ NPREEREPSM GQKLEILIKD TLGLPVAGQT SEFVNQVLGK TAEGNPTGGL VGLRIPASKV
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response (UPR). Represses the transcriptional activity of CREB3 during the UPR. Recruits CREB3 into nuclear foci.
  • 基因功能參考文獻：
    1. LRF has a role in the process of implantation in uteri and development of preimplantation embryos in mice PMID: 23400243
    2. postulate that LRF plays a critical role in the attenuation of the HPA axis through repression of glucocorticoid stress signaling during parturition and the postpartum period PMID: 23071095
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    BZIP family, CREBRF subfamily
  • 組織特異性：
    Highly expressed in intestin, testis, heart and kidney, weakly in brain adipose, colon, liver, lung and skeletal.
  • 數(shù)據(jù)庫鏈接：

    KEGG: mmu:77128

    UniGene: Mm.275414