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  4. Recombinant Mouse Putative methyltransferase NSUN3 (Nsun3)

Recombinant Mouse Putative methyltransferase NSUN3 (Nsun3)

  • 中文名稱：
    小鼠Nsun3重組蛋白
  • 貨號：
    CSB-YP805563MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Nsun3重組蛋白
  • 貨號：
    CSB-EP805563MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Nsun3重組蛋白
  • 貨號：
    CSB-EP805563MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Nsun3重組蛋白
  • 貨號：
    CSB-BP805563MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Nsun3重組蛋白
  • 貨號：
    CSB-MP805563MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Nsun3
  • Uniprot No.：
  • 別名：
    Nsun3; tRNA; cytosine(34)-C(5))-methyltransferase; mitochondrial; EC 2.1.1.-; NOL1/NOP2/Sun domain family member 3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-348
  • 氨基酸序列
    MLTRLKAKSE GKLAKQLCRV VLDQFDKQYS KELGDSWSTV RDVLISPSLW QYAILFNRFN YPFELEKALH LRGYHTVLQG ALPHYPKSMK CYLSRTPDRM PSERHQTGSL KKYYLLNAAS LLPVLALELR DGEAVLDLCA APGGKSVALL QCAYPGYLLC NEYDRPRGRW LRQTLESFIP QPLINVIKVS ELDGREMGDA QPATFDKVLV DAPCSNDRSW LFSSDSQKAA YRIHQRKNLP VLQVELVRSA IKALRPGGLL VYSTCTLSKA ENQDVISEVL TSDSNIVPVD ISGIARTFSQ DFTFAPTDQK CSLLVIPEKG KAWGPMYIAK LKKGMSTRKR QGEFCKPC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt-tRNA(Met). mt-tRNA(Met) methylation at cytosine(34) takes place at the wobble position of the anticodon and initiates the formation of 5-formylcytosine (f(5)c) at this position. mt-tRNA(Met) containing the f(5)c modification at the wobble position enables recognition of the AUA codon in addition to the AUG codon, expanding codon recognition in mitochondrial translation.
  • 基因功能參考文獻：
    1. Nsun3 regulates embryonic stem cell differentiation by promoting mitochondrial activity. PMID: 29103146
  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
  • 數(shù)據(jù)庫鏈接：