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  4. Recombinant Mouse Tectonic-1 (Tctn1)

Recombinant Mouse Tectonic-1 (Tctn1)

  • 中文名稱：
    小鼠Tctn1重組蛋白
  • 貨號(hào)：
    CSB-YP804890MO
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Tctn1重組蛋白
  • 貨號(hào)：
    CSB-EP804890MO
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Tctn1重組蛋白
  • 貨號(hào)：
    CSB-EP804890MO-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Tctn1重組蛋白
  • 貨號(hào)：
    CSB-BP804890MO
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Tctn1重組蛋白
  • 貨號(hào)：
    CSB-MP804890MO
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Tctn1
  • Uniprot No.：
  • 別名：
    Tctn1; Tect1; Tectonic-1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    23-593
  • 氨基酸序列
    QVIAIPAA ATPAVTKEDL NSTKATPTTL QPSLSPRTPG TPRAPERSGP RPTPVTDVAA LCVCDLLPAQ CDVNCCCDPD CSPADFSIFS ACSVPVVTGD RQFCSQKAAF YSMNLTADPP HRDFKLIDQI NPSVFCIHIS NYKPALSFAN PEVPDENNFD RLMQTSGGFT LSAESAVPST AASDGPQPTK YEYGAPLQTA GASSGSFLKL PSPLTSSLCA DQNPAAFLVS QAFECSRRVD IEQCEGMEAL SMAHYSSPAI LRVPNSMTQV SIKIQSVMYR SLNHTLTQLE GHGVLRPSLV STGQDRLCSN VVLQVKYSLL YTATGQIHEA GLSLVLGTLS SAVSLLQQKF EIHFIQHGTK PVPLSGNPGY RVGLPLAAGF QPQKGSGIIQ TTNRQGQFTI LRSTSQQDCL ASEGLRTPVL FGYNVQSGCQ LRLTGTIPCG LLAQKVQDLL RGQAFPDYVA AFGNSRAQDV QDWVPVHFVT YSSNMKGSCQ LPVALAIEVK WTKYGSLLNP QARIVNVTAQ LVSVPEPLPG PERTVVISTA VTFVDVSAPA EAGFRAPPTI NARLPFSFFF PFV
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23.
  • 基因功能參考文獻(xiàn)：
    1. Loss of Tctn1 is associated with ciliopathies. PMID: 21725307
    2. During neural tube development, mouse Tectonic is required for formation of the most ventral cell types and for full Hedgehog (Hh) pathway activation. Tectonic plays an additional role in repressing Hh pathway activity. PMID: 16357211
  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton, cilium basal body. Secreted.
  • 蛋白家族：
    Tectonic family
  • 數(shù)據(jù)庫(kù)鏈接：