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Recombinant Mouse Thrombospondin-1 (Thbs1),Partial

In Stock
  • 中文名稱：
    小鼠Thbs1重組蛋白
  • 貨號(hào)：
    CSB-EP023487MO
  • 規(guī)格：
    ￥1836
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
  • Uniprot No.：
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Partial
  • 來(lái)源：
    E.coli
  • 分子量：
    40.6kDa
  • 表達(dá)區(qū)域：
    19-350aa
  • 氨基酸序列
    NRIPESGGDNGVFDIFELIGGARRGPGRRLVKGQDLSSPAFRIENANLIPAVPDDKFQDLLDAVWADKGFIFLASLRQMKKTRGTLLAVERKDNTGQIFSVVSNGKAGTLDLSLSLPGKQQVVSVEEALLATGQWKSITLFVQEDRAQLYIDCDKMESAELDVPIQSIFTRDLASVARLRVAKGDVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSATNVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGLSCDELSSMVLELKGLRTIVTTLQDSIRKVTEENRELVSELKRPPLCFHNGVQYKNNEEWTVDSCTECHCQNSVTICK
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白標(biāo)簽：
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產(chǎn)品描述：

    A cDNA ORF corresponding to the peptide of Mouse Thrombospondin-1/Thbs1 was expressed with an N-terminal 6xHis-tag in E.coli. Thrombospondin-1/Thbs1 CSB-EP023487MO is a truncated molecule having amino acids of Asn19-Lys350. Its purity is greater than 90% as measured by SDS-PAGE. A molecular mass band of 41 about kDa was presented on the SDS-PAGE gel under reducing conditions. And in-stock Thbs1 proteins are available now. In addition to producing specific antibodies, this recombinant Thbs1 proteins may also be used on the studies of glioblastoma (GBM).

    Thbs1 is an important component of the extracellular matrix (ECM) that exerts a role in tumor development and metastasis. The expression level of Thbs1 is positively correlated with the glioma grades, that is, the more severe the glioma, the higher the expression level of Thbs1. TGFβ1 regulates Thbs1 expression via SMAD3-binding sites. Thbs1 in GBM is involved in the disruption of GBM growth ＆vascularisation, tumor invasion, and expansion. Silencing Thbs1 alone or in combination with anti-angiogenic therapy can inhibit tumor invasion and proliferation.

  • Datasheet & COA：
    Please contact us to get it.

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