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  4. Recombinant Rat Linker for activation of T-cells family member 2 (Lat2), partial

Recombinant Rat Linker for activation of T-cells family member 2 (Lat2), partial

  • 中文名稱：
    大鼠Lat2重組蛋白
  • 貨號：
    CSB-YP805585RA
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Lat2重組蛋白
  • 貨號：
    CSB-EP805585RA
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Lat2重組蛋白
  • 貨號：
    CSB-EP805585RA-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Lat2重組蛋白
  • 貨號：
    CSB-BP805585RA
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Lat2重組蛋白
  • 貨號：
    CSB-MP805585RA
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Lat2
  • Uniprot No.：
  • 別名：
    Lat2; Lab; Ntal; Wbscr5; Linker for activation of T-cells family member 2; Linker for activation of B-cells; Non-T-cell activation linker
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
  • 基因功能參考文獻：
    1. These results suggest that increased asymmetric dimethylarginine (ADMA) efflux mediated by upregulated yLAT2 may be a mechanism by which ammonia interferes with intra-astrocytic (and possibly intra-endothelial cell) ADMA content and subsequently, NO synthesis in both cell types. PMID: 29099056
    2. Up-regulation of y(+)LAT2 transporter is coupled with increased inducible nitric oxide synthase (iNOS) expression PMID: 26448619
    3. The Saturday night forecast called for possible showers or thunderstorms, with winds of 20 to 26 mph. The expected total rainfall Saturday ranges from six-tenths of an inch to an inch, with more possible in thunderstorms, the weather service said. PMID: 21403644
    4. Regulates Fc epsilon type I (IgE) receptor-mediated signaling at multiple steps and by different mechanisms in mast cells. PMID: 17911602
    5. LAT2 and LAT1 form separate membrane microdomains in rat basophilic leukemia cells. PMID: 15477348
    6. LAT2 colocalizes with Thy-1 (CD90); their colocalization is enhanced following Thy-1 aggregation. PMID: 17013982

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  • 亞細胞定位：
    Cell membrane; Single-pass type III membrane protein.
  • 數(shù)據(jù)庫鏈接：