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  4. Recombinant Saccharomyces cerevisiae Heat shock protein SSA2 (SSA2), partial

Recombinant Saccharomyces cerevisiae Heat shock protein SSA2 (SSA2), partial

  • 中文名稱：
    釀酒酵母SSA2重組蛋白
  • 貨號：
    CSB-YP318771SVG
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母SSA2重組蛋白
  • 貨號：
    CSB-EP318771SVG
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母SSA2重組蛋白
  • 貨號：
    CSB-EP318771SVG-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母SSA2重組蛋白
  • 貨號：
    CSB-BP318771SVG
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母SSA2重組蛋白
  • 貨號：
    CSB-MP318771SVG
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SSA2
  • Uniprot No.：
  • 別名：
    SSA2; YLL024C; L0931Heat shock protein SSA2
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    May play a role in the transport of polypeptides both across the mitochondrial membranes and into the endoplasmic reticulum. A functional difference between SSA1 and SSA2 proteins is expected. SSA2 can participate in the ATP-dependent disassembly of clathrin-coated vesicles.
  • 基因功能參考文獻：
    1. Molecular chaperones of the Hsp70 family, SSA1 and SSA2, assist in the assembly of 20S proteasomes. PMID: 28322792
    2. Ssa1 and Ssa2 are both necessary for the degradation of short-lived proteins. Ssa1 stably associates with its substrates and promotes their ubiquitylation. PMID: 27178214
    3. SSA2p and co-chaperones, SIS1p and YDJ1p, constitute a novel system for tRNA import into the nucleus. PMID: 25853343
    4. SIS1 is required for the targeting of misfolded proteins to the ubiquitylation machinery, whereas the decision to degrade or sequester ubiquitylated proteins is mediated by SSA1 and SSA2. PMID: 23637465
    5. little difference in ATPase, protein refolding, and amyloid inhibiting activities of purified Ssa1p and Ssa2p, but interchanging NBD residue alanine 83 (Ssa1p) and glycine 83 (Ssa2p) switched functions of Ssa1p and Ssa2p PMID: 21808014
    6. activity of purified cucumber necrosis tombusvirus (CNV) replicase correlated with viral RNA replication in the ssa1 ssa2 mutant and in the Ssa overexpression strains, suggesting that Ssa1/2p plays an important role in the assembly of the CNV replicase PMID: 16474124
    7. A genetic screen that identifies an array of mutants within the two major cytosolic Hsp70 chaperones of yeast, Ssa1p and Ssa2p, which impair the propagation of [PSI+], is reported. PMID: 17151238
    8. Ssa1/2p might contribute to chromosomal control in yeast PMID: 17691831

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  • 亞細胞定位：
    Cytoplasm. Secreted, cell wall.
  • 蛋白家族：
    Heat shock protein 70 family
  • 數(shù)據(jù)庫鏈接：

    KEGG: sce:YLL024C

    STRING: 4932.YLL024C