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  4. Recombinant Xenopus laevis T-box transcription factor TBX6 (tbx6), partial

Recombinant Xenopus laevis T-box transcription factor TBX6 (tbx6), partial

  • 中文名稱：
    有爪蟾蜍tbx6重組蛋白
  • 貨號(hào)：
    CSB-YP805208XBE
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    有爪蟾蜍tbx6重組蛋白
  • 貨號(hào)：
    CSB-EP805208XBE
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    有爪蟾蜍tbx6重組蛋白
  • 貨號(hào)：
    CSB-EP805208XBE-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    有爪蟾蜍tbx6重組蛋白
  • 貨號(hào)：
    CSB-BP805208XBE
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    有爪蟾蜍tbx6重組蛋白
  • 貨號(hào)：
    CSB-MP805208XBE
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    tbx6
  • Uniprot No.：
  • 別名：
    tbx6; T-box transcription factor TBX6; T-box protein 6; XTbx6
  • 種屬：
    Xenopus laevis (African clawed frog)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Transcriptional activator. Plays a role in ventral mesoderm specification and acts together with nog during muscle differentiation. Mediates posterior pattern formation of the embryo, including specification of posterior mesoderm, via activation of the Wnt and Fgf signaling pathways.
  • 基因功能參考文獻(xiàn)：
    1. Tbx6 is required for neural crest and intermediate mesoderm development in Xenopus PMID: 20083100
    2. several signaling pathways are involved in regulating Tbx6 expression in the initiation of myogenesis PMID: 15188053
    3. FGF8, Wnt8 and Myf5 are target genes of Tbx6 during anteroposterior specification in Xenopus embryo PMID: 16343478
    4. Data show that morpholino-induced knockdown of Xenopus Tbx6 impairs posterior development, indicating the requirement of XTbx6 in this process. PMID: 16953215
    5. Based on our findings, we conclude that a part of the transcriptional repression at the anterior end of the PSM is caused by Bowline mediated transcriptional repression of Tbx6-dependent gene expression in X. laevis. PMID: 17577580
    6. These results indicate that the appropriate expression of bowline/Ripply2 is regulated by a direct interaction between the Tbx6 and mespb proteins during Xenopus somitogenesis. PMID: 18510946
    7. Xtbx6 is a direct regulator of pMesogenin1 and 2, which are both involved in somitogenesis and myogenesis including that of body wall muscle in Xenopus laevis PMID: 19035338

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  • 亞細(xì)胞定位：
    Nucleus.
  • 組織特異性：
    At gastrulation, expressed in the lateral and ventral mesoderm. Expressed around the blastopore except at the dorsal midline. As gastrulation proceeds, expression extends anteriorly and ventrally. At the tailbud stage, expression then retracts caudally be
  • 數(shù)據(jù)庫鏈接：

    KEGG: xla:394428

    UniGene: Xl.7697