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Recombinant Xenopus laevis Tyrosyl-DNA phosphodiesterase 2 (tdp2)

  • 中文名稱：
    有爪蟾蜍tdp2重組蛋白
  • 貨號：
    CSB-YP398902XBE
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    有爪蟾蜍tdp2重組蛋白
  • 貨號：
    CSB-EP398902XBE
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    有爪蟾蜍tdp2重組蛋白
  • 貨號：
    CSB-EP398902XBE-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    有爪蟾蜍tdp2重組蛋白
  • 貨號：
    CSB-BP398902XBE
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    有爪蟾蜍tdp2重組蛋白
  • 貨號：
    CSB-MP398902XBE
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    tdp2
  • Uniprot No.：
  • 別名：
    tdp2; ttrap; Tyrosyl-DNA phosphodiesterase 2; Tyr-DNA phosphodiesterase 2; EC 3.1.4.-; 5'-tyrosyl-DNA phosphodiesterase; 5'-Tyr-DNA phosphodiesterase; TRAF and TNF receptor-associated protein homolog
  • 種屬：
    Xenopus laevis (African clawed frog)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-371
  • 氨基酸序列
    MEVEEAGAVQ TGTGEAVVAN ERTKQCSAFA SITGCDEAVA QCFLAENDWD MERAINSYFE PGVESTLQNK PAADLADPLK QEMHAVTSDA CIDLTSDDLV ATKSEAVTSN SSTVKQQEDE SHFTFLTWNI DGLDESNVAE RARAVCSCLA LYTPDVVFLQ EVIPPYCEYL KKRAVSYKII TGNEDEYFTA MMLKKSRVKL ISQEIVPYPS TLMMRNLLVA NVNISGNSIC LMTSHLESTK DHSKERLKQL DTVLKKMMDA PPSATVIFGG DTNLRDQEVA KIGGLPNTIL DVWEFLGKPE HCRYTWDTKL NNNLRACYTS RLRFDRILYR ASMEGSQVIP QFLNLVGTEK LDCGRFPSDH WGLLCDFDII L
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (top2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals.
  • 亞細胞定位：
    Nucleus. Nucleus, PML body.
  • 蛋白家族：
    CCR4/nocturin family, TTRAP/TDP2 subfamily
  • 數(shù)據(jù)庫鏈接：

    KEGG: xla:100049743

    UniGene: Xl.8025