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  4. Recombinant Xenopus laevis Zinc finger protein 36, C3H1 type-like 2-B (zfp36l2-B)

Recombinant Xenopus laevis Zinc finger protein 36, C3H1 type-like 2-B (zfp36l2-B)

  • 中文名稱：
    有爪蟾蜍zfp36l2-B重組蛋白
  • 貨號：
    CSB-YP773869XBE
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    有爪蟾蜍zfp36l2-B重組蛋白
  • 貨號：
    CSB-EP773869XBE
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    有爪蟾蜍zfp36l2-B重組蛋白
  • 貨號：
    CSB-EP773869XBE-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    有爪蟾蜍zfp36l2-B重組蛋白
  • 貨號：
    CSB-BP773869XBE
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    有爪蟾蜍zfp36l2-B重組蛋白
  • 貨號：
    CSB-MP773869XBE
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    zfp36l2-B
  • Uniprot No.：
  • 別名：
    zfp36l2-B; zfp36l2; mRNA decay activator protein ZFP36L2-B; CCCH zinc finger protein 3-B; XC3H-3b; Zinc finger protein 36; C3H1 type-like 2-B
  • 種屬：
    Xenopus laevis (African clawed frog)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-364
  • 氨基酸序列
    MSTTLLSAFY DIDLLYKNEK ALNNLALSTM LDKKAVGSPV SSTNSNLFPG FLRRHSATNL QALSGSTNLA KFCPNNNNNP LKDPAVSSTA LLNRENKFRD RSFSENGERS QHLLHLQQQQ QQQKAGAQVN STRYKTELCR PFEENGACKY GEKCQFAHGF HELRSLTRHP KYKTELCRTF HTIGFCPYGP RCHFIHNAEE RRQAPGAGER PKLHHSLSFS GFPNHSLDSP LLESPTSRTP PPQSSGSLYC QELLQLNNNN PCANNAFTFS GQELGLIAPL AIHTQNQSYC RQPCSSPPLS FQPLRRVSES PVFDAPPSPP DSLSDRDSYL SGSLSSGSLS GSDSPTLDSN RRLPIFSRLS ISDD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs. Induces also the degradation of ARE-containing mRNAs even in absence of poly(A) tail. Required for tubulogenesis during pronephros development.
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 組織特異性：
    Remains unlocalized in the egg and early embryo. From stage 21 (late neurula), expressed around the pronephros in the anterior crests, pharyngeal arch, hindbrain, mesodermal tissues around the pronephros and tail-bud. This expression pattern is maintained
  • 數(shù)據(jù)庫鏈接：

    KEGG: xla:398103

    UniGene: Xl.476