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Recombinant Guinea pig Integrin beta-6 (ITGB6)

  • 中文名稱：
    Recombinant Guinea pig Integrin beta-6(ITGB6)
  • 貨號：
    CSB-CF011890GU
  • 規(guī)格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產(chǎn)品詳情

  • 基因名：
  • Uniprot No.：
  • 別名：
    ITGB6; Integrin beta-6; Fragment
  • 種屬：
    Cavia porcellus (Guinea pig)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-577
  • 氨基酸序列
    SASMDDDLNTIKELGSLLSKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEEIANPCSSIP YICLPTFGFKHILPLTNDAERFNEIVKKQKISANIDNPEGGFDAIMQAAVCKEKIGWRND SLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDSKNEYSMSTVMEYPTIGQLIDKVVQ NNVLLIFAVTQEQVPLYENYAKLIPGATVGLLHKDSGNILQLIISAYEELRSEVELEVLG DTEGLNLSFSAVCNNGTLFPHQKKCLHMKVGETASFNVTVSIPNCERKSRHVIIKPVGLG DTLEILVSPECSCDCQKEVEVNSSKCHNGNGSYQCGVCACNPGHMGPHCECGEDTLSTDS CKETPDHPSCSGRGDCYCGQCICHLSPYGNIYGPYCQCDNFSCVRHKGLLCGDNGDCECG ECVCRSGWTGEYCNCTTSTDTCISEDGTLCSGRGDCVCGKCVCTNPGASGPTCERCPTCS DPCNSKRSCIECHLSADGQPGEECVDKCKLAGVTISKEADFSKDSSVSCSLQGENECLIT FLISTDNEGKTIIHNISEKDCPKPPNIPMIMLGVSLA
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白標(biāo)簽：
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation.
  • 亞細(xì)胞定位：
    Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion.
  • 蛋白家族：
    Integrin beta chain family
  • 數(shù)據(jù)庫鏈接：