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Recombinant Saccharomyces cerevisiae CDP-diacylglycerol--inositol 3-phosphatidyltransferase (PIS1)

  • 中文名稱：
    釀酒酵母PIS1重組蛋白
  • 貨號：
    CSB-CF005059SVG
  • 規(guī)格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產(chǎn)品詳情

  • 基因名：
    PIS1
  • Uniprot No.：
  • 別名：
    PIS1; PIS; YPR113W; P8283.5; CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Phosphatidylinositol synthase; PI synthase; PtdIns synthase
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-220
  • 氨基酸序列
    MSSNSTPEKVTAEHVLWYIPNKIGYVRVITAALSFFVMKNHPTAFTWLYSTSCLLDALDG TMARKYNQVSSLGAVLDMVTDRSSTAGLMCFLCVQYPQWCVFFQLMLGLDITSHYMHMYA SLSAGKTSHKSVGEGESRLLHLYYTRRDVLFTICAFNELFYAGLYLQLFSNSATFGKWTT IISFPGYVFKQTANVVQLKRAALILADNDAKNANEKNKTY
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白標簽：
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 基因功能參考文獻：
    1. Cytosolically made inositol and CDP-diacylglycerol can access the active site of the yeast PI synthase Pis1 from the cytosolic side and that Pis1 structure is strongly affected by mild detergents. PMID: 25687304
    2. This study employed a genomic screen, database mining, and more traditional promoter analysis to identify genes that affect PIS1 expression. PMID: 15755922
    3. PIS1-encoded phosphatidylinositol synthase in Saccharomyces cerevisiae is regulated by zinc PMID: 15980062
    4. Enhanced phosphatidylinositol synthesis may account for PIS1 suppression of rsp5 defects. PMID: 16363994
    5. multiple upstream AUG codons are present in at least some PIS1 transcripts and negatively impact PIS1 expression PMID: 16997274

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  • 亞細胞定位：
    Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein.
  • 蛋白家族：
    CDP-alcohol phosphatidyltransferase class-I family
  • 數(shù)據(jù)庫鏈接：

    KEGG: sce:YPR113W

    STRING: 4932.YPR113W