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  4. Recombinant Salmonella typhimurium Magnesium transport protein CorA (corA)

Recombinant Salmonella typhimurium Magnesium transport protein CorA (corA)

  • 中文名稱：
    Recombinant Salmonella typhimurium Magnesium transport protein CorA(corA)
  • 貨號：
    CSB-CF363297SXB
  • 規(guī)格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產(chǎn)品詳情

  • 基因名：
    corA
  • Uniprot No.：
  • 別名：
    corA; STM3952; STMD1.38; Magnesium transport protein CorA
  • 種屬：
    Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-316
  • 氨基酸序列
    MLSAFQLEKNRLTRLEVEESQSLIDAVWVDLVEPDDDERLRVQSELGQSLATRPELEDIE ASARFFEDEDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLFTLRERELPAFRLYRMRAR SQAMVDGNAYELLLDLFETKIEQLADEIENIYSDLEKLSRVIMEGHQGDEYDEALSTLAE LEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQAREILRDIESLLPHNESLFQKVNFL MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELKWSFGYPGAIIFMI LAGLAPYLYFKRKNWL
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白標(biāo)簽：
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Mediates both influx and efflux of magnesium ions. Can also mediate cobalt and nickel uptake, albeit only at extracellular concentrations that are toxic to the cell. Does not transport iron. Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high.
  • 基因功能參考文獻(xiàn)：
    1. Overexpression of the Mg(2+) transporter CorA, which is believed to increase cytoplasmic Mg(2+) levels, decreased mgtA transcription in a manner dependent on a functional mgtA 5' leader. PMID: 19897653
    2. does not transport Fe2+ and that the relationship, if any, between iron toxicity and corA is indirect PMID: 15516579
    3. affects lactoperoxidase sensitivity but not other oxidative stress PMID: 16269676
    4. Data show that a corA mutant is attenuated in mice and defective for invasion of and replication within epithelial cells PMID: 18676664
    5. Data show that loss of the CorA protein disrupts a regulatory network(s) with the ultimate phenotype of decreased virulence PMID: 18676666

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  • 亞細(xì)胞定位：
    Cell inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    CorA metal ion transporter (MIT) (TC 1.A.35) family
  • 數(shù)據(jù)庫鏈接：

    KEGG: stm:STM3952

    STRING: 99287.STM3952