Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 跨膜蛋白
  4. Recombinant Streptococcus pneumoniae Sensor protein CiaH (ciaH)

Recombinant Streptococcus pneumoniae Sensor protein CiaH (ciaH)

  • 中文名稱：
    Recombinant Streptococcus pneumoniae Sensor protein CiaH(ciaH)
  • 貨號(hào)：
    CSB-CF358534SMP
  • 規(guī)格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產(chǎn)品詳情

  • 基因名：
    ciaH
  • Uniprot No.：
  • 別名：
    ciaH; spr0708; Sensor protein CiaH
  • 種屬：
    Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-444
  • 氨基酸序列
    MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLYTSVDDKLHGLSENPQA VIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFDKDFTQLLSGNRFLGLDKI KLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTNIKYAAVLINTSQLEQASQKH EQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQSFVENASHELRTPLAVLQNRLE TLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLNLARRDDGIKPELAEVPTSFFNTTF TNYEMIASENNRVFRFENRIHRTIVTDQLLLKQLMTILFDNAVKYTEEDGEIDFLISATD RNLYLLVSDNGIGISTEDKKKIFDRFYRVDKARTRQKGGFGLGLSLAKQIVDALKGTVTV KDNKPKGTIFEVKIAIQTPSKKKK
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白標(biāo)簽：
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Member of the two-component regulatory system CiaH/CiaR. Involved in early steps of competence regulation and in penicillin susceptibility. Probably phosphorylates CiaR.
  • 基因功能參考文獻(xiàn)：
    1. A hyperactive CiaRH system prevents competence development by csRNA-dependent post-transcriptional repression of CSP (competenece stimulating peptide) production. PMID: 23710838
    2. All mutant ciaH alleles enhanced CiaR-mediated gene expression beyond wild-type levels. PMID: 21903754
    3. CiaH may act as a kinase or phosphatase and CiaR is apparently able to obtain its phosphate independently of CiaH. PMID: 21422763
  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 數(shù)據(jù)庫鏈接：

    KEGG: spr:spr0708

    STRING: 171101.spr0708